DASbox® Mini Bioreactor System
The DASbox is a unique mini bioreactor system suitable for microbial and cell culture as well as stem cell applications. It is designed as a 4-fold system with up to twenty-four parallel operating bioreactors. With working volumes of 60 – 250 mL the DASbox is the optimal tool for advanced process development and Design of Experiments (DoE) applications. All critical process parameters can be precisely controlled. Liquid-fre…
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The DASbox is a unique mini bioreactor system suitable for microbial and cell culture as well as stem cell applications.
It is designed as a 4-fold system with up to twenty-four parallel operating bioreactors. With working volumes of 60 – 250 mL the DASbox is the optimal tool for advanced process development and Design of Experiments (DoE) applications. All critical process parameters can be precisely controlled. Liquid-free temperature control and exhaust condensation satisfy users with easy handling.
In addition to using industry standard glass bioreactors the DASbox can be equipped with Eppendorf BioBLU® 0.3 vessels, all fully instrumented single-use mini bioreactors.
Eppendorf DASbox® Mini Bioreactor System Features:
- Parallel set-up of up to 24 bioreactors;
- Excellent scalability and reproducibility in both microbial and cell culture applications;
- Supports industry standard glass bioreactors (DASbox Mini Bioreactor) as well as the BioBLU 0.3 Single-Use Vessels;
- Small working volumes save on the amount of cell material, media and supplements required;
- Extremely compact system with a footprint of only 7.5 cm (3 in) benchspace per vessel;
- Individual temperature control with liquid-free heating and cooling (Peltier);
- Liquid-free Peltier exhaust condenser with easy handling by automatic slide in activation and slide out deactivation mode;
- LC display with key process parameters and integrated alarm function simplifies monitoring;
- Fully mass flow-controlled gas mixing with individual gas mixture from Air, O2, CO2 and N2, each directable either to headspace or sparger;
- Standard sensors for precise measurement and control of temperature, pH, DO, level and ORP (redox potential); optical pH sensors available;
- Precise miniature variable speed pumps, continuous flow rates down to 0.3 mL/h;
- Sealed magnetic overhead drives for single-use vessels and direct overhead drives for autoclavable vessels; up- or downflow selectable;
- Optional pull-out system for enhanced accessibility of bioreactors and control unit.
Applications:
- Process development in cell culture and microbiology;
- Design of Experiments (DoE) Media optimization Clone and cell line screening, strain characterization.
Transforming bioprocess data into actionable intelligence
Managing the weight of bioprocessing data can often overwhelm laboratories, but effective data management is both achievable and critical to successful biopharmaceutical development.
This application eBook highlights advanced instruments and digital tools that integrate seamlessly into laboratory infrastructure, enabling continuous monitoring and streamlined data management. With remote accessibility, these solutions empower scientists to maintain oversight and control of bioprocessing data beyond the physical lab environment.
Download to learn:
- How to conduct accurate and efficient real-time monitoring of Chinese hamster ovarian (CHO) cultivation using the BioNsight®
- Case studies using automated technologies for sampling CHO and E.coli cultures to understand growth conditions, and improve experimental throughput.
- The potential of Raman spectroscopy to accurately track critical process parameters
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Stem cell derived exome production in stirred-tank bioreactors
In this video, Eppendorf introduces exosomes as a promising cell-free therapy tool and describes the challenges behind the exosome production process.
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Discover how the latest innovations in upstream bioprocessing are serving the cell and gene therapy industry
