Morphologi 4
Rapid, automated particle size and particle shape analysis
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Morphologi 4 provides detailed morphological descriptions of particulate samples through static image analysis, enabling a greater understanding of both sample and process. It can equally be used as an R&D tool to investigate challenging applications and in automated QC analysis where generation of robust, user-independent results and validation are required.
- Broad particle size range, from 0.5 μm to over >1300 μm, enables size measurements of a wide range of samples
- 20+ morphological parameters deliver a highly-detailed description for deeper understanding of your particulate material
- SOP control, from sample dispersion to data analysis, provides simple and automated operation for robust, repeatable measurements
- Automated ‘Sharp Edge’ analysis enables detection of even low contrast particles
- Advanced manual microscope mode and ability to return to particles of interest enables an even closer examination of unexpected particles
- High resolution microscope ensures quality particle images for optimum image analysis data
- Integrated dry powder dispersion unit delivers reproducible sample dispersion, critical to achieving meaningful results
- Dedicated sample presentation accessories enable measurement of a wide variety of sample types, including suspensions and filters
- Advanced data exploration tools generate maximum sample knowledge
- 21 CFR Part 11 software option ensures regulatory compliance
Grating-coupled interferometry – the weak fragment hit biosensor assay
Grating-coupled interferometry (GCI) is ideally suited for fragment-based drug discovery due to inherent sensitivity of the detection principle, and the ability to capture fast transitions. It uses the refractive index changes that occur with protein binding and are measured as time-dependent phase-shift signals. Explore how the Creoptix® WAVEsystem combines GCI with innovative no-clog microfluidics, permitting the study of biomolecular interactions using crude, unpurified samples, or in complex matrices, such as serum, plasma, or cell supernatant. The WAVEsystem uses a robust sensor and microfluidics cartridge, the WAVEchip®, with four parallel flow channels, available in different surface matrix chemistries suitable for diverse applications, such as protein, antibody, VLPs, lipids, and others.
