Nanosight Pro
Characterizing Nano- and Biomaterials has never been so quick, easy, and accurate.
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I found the NanoSight LM 20 highly effective and easy to use for exosome characterization, providing specific data.
Exosome characterization
I have used your NanoSight LM 20 for the characterization of exosomes. It provided excellent insights into the size and concentration of exosomes, and it was very easy to use. The results were highly specific and logical. Recently, I noticed that you have launched an advanced version, NanoSight Pro. I am interested in purchasing it to further advance my research on bionanoparticles/exosomes. This is truly an excellent instrument for determining the size and concentration of exosomes and other bionanoparticles.
Review Date: 28 Mar 2025 | Malvern Panalytical
Manufacturer's Response
Thank you for your kind feedback! We're thrilled to hear that the NanoSight instrument has been a valuable tool in your research over the years. We’re confident that you’ll be equally impressed with the newest system and the advanced capabilities it offers. Please feel free to reach out if you have any questions or need assistance with the new system.
Recommended Buy
Nanobubbles
Value for money. Easy to use & provides consistent results.
Review Date: 28 Mar 2025 | Malvern Panalytical
Manufacturer's Response
Dear Customer, thank you for your feedback. We’re happy to hear that you find the NanoSight easy to use and that it delivers consistent results. We're committed to making your experience as seamless as possible, and it's wonderful to know the system is meeting your expectations.
Works well for sizing and quantifying LNPs and adenovirus
LNP and Adenovirus characterization
I've been using the Nanosight Pro for several months now to characterize LNPs and adenovirus both around 100 nm. Overall, my experience has been positive. There are definitely some challenges that come up and require experience. I've contacted support multiple times which have been good experiences. Pros: works great for quantifying and sizing my particles. Results can be reproducible. The video is useful and allowed us to see some unusual aggregate chains. Running samples is straight forward. Cons: Running samples can be problematic if unaware of potential problems. Air bubbles are the biggest problem. These can be very difficult to remove sometimes and must be checked for after loading a sample. Thorough washing between samples can be required depending on the sample. The fluorescence capability is nice but so far particle brightness seems lacking. Particle bleaching was also observed. You can reverse the flow to reduce bleaching but I have not tried it. Other thoughts: I have found some LNPs require washing with detergent after a few samples because (I suspect) lipids are sticking to the plastic and degrading the image sharpness. The concentration (particles/ml) also needs to be optimized for your sample to get an accurate count and minimize carryover between samples.
Review Date: 9 Oct 2024 | Malvern Panalytical
Rapid running with the easy method, and show great results!
Analyze the nanoscale materials, e.g. lipid-based nanoparticles.
The software is not complicated; it saves time for training the new users and running the experiments. It has autofocus and a camera that is easy and convenient. Also, the data was precise and accurate.
Review Date: 7 Nov 2023 | Malvern Panalytical
Great results, this will provide valuable data for many investigators
Analyze extracellular vesicles
We purchased this instrument for our core laboratory. It will be utilized by several investigators for viral and extracellular vesicle research. There is not another instrument on campus that would provide the data that this does. It is easy to use and importantly automate for walk away use. The training was outstanding and the instrument is easy to care for.
Review Date: 17 Mar 2023 | Malvern Panalytical
Great
analyze the size of nanoparticle and exosome
It is quite easy to use and the results are reliable. We will purchase the product of Malvern Panalytical again in the future.
Review Date: 13 Feb 2023 | Malvern Panalytical
Manufacturer's Response
It’s great to hear you are happy with Malvern Panalytical product and that NanoSight NS300 is providing you with the data you can rely on.
With the introduction of the NanoSight Pro, Malvern Panalytical provides the best in class, simple and rapid NTA solution for nano- and biomaterials characterization.
The combination of advanced engineering and a blend of smart features assures NTA measurements are efficient, quick, and accessible to all users. Powered by machine learning, NS Xplorer software enables automated measurements, removes subjectivity, and provides the highest quality size and concentration data for both, the light scatter and fluorescence analysis.
Interchangeable lasers allow application flexibility, whilst Smart Manager connection assures robustness without a worry for quality issues or downtime.
Features
- Quick install & analysis: NanoSight Pro can be used by every user in every lab. Smart installation allows you to get up and running quickly. With minimum setup, easy operation and intuitive NS Xplorer software you can measure your samples in minutes.
- Intelligent & automated: Powered by machine learning and intelligent features, NanoSight Pro automates processing and eliminates human error, delivering superior particle identification and precise particle tracking for the highest quality and reproducible data.
- Highest resolution: The NanoSight Pro measures nanoscale particles in the range of 10 nm - 1000 nm including low scattering and biological particles. Particle–by–particle analysis assures high resolution size and concentration data with visual confirmation.
- Power of fluorescence: In addition to light scatter, fluorescence signals can be detected from fluorescently tagged biologics or synthetic particles providing even greater insight into your sample. Interchangeable laser modules with the choice of four excitation wavelengths can be used along with the matching long pass filters for the optimum setup supported by analysis in flow for better sampling and tracking of even photobleaching samples.
MIP Discovery case study
In this video, Oliver Huseyin from MIP Discovery demonstrates his use of NanoSight Pro for developing and quality-assuring molecularly imprinted polymers (MIP) used in sensors and COVID-19 lateral flow tests. He relies on NanoSight Pro to accurately size his MIP population, ensuring effective MIP conjugation and batch consistency. Huseyin highlights the quick setup and analysis process with NanoSight Pro, emphasizing its advantages over NS300 technology.
NanoSight Pro: Expert nanoparticle tracking analysis
In this video, Malvern Panalytical introduces NanoSight Pro, a cutting-edge solution for characterizing bio and nanomaterials. NanoSight Pro provides quick and detailed access to high-resolution size and concentration data, offering particle-by-particle tracking precision through Brownian motion. Its unique optical system ensures repeatable and superior data quality, enabling a deep understanding of complex systems. Combined with fluorescence capabilities and powered by machine learning, NanoSight Pro automates workflows, eliminating subjectivity and human error.
NanoSight Pro launch highlights
In this video, Malvern Panalytical provides highlights from the launch event of the NanoSight Pro. NanoSight Pro provides access to high-resolution size and concentration data, revealing individual nano-scale traces through Brownian motion. This technology offers particle-by-particle tracking precision, decoding the complexity of various systems. Enhanced by its unique optical system, NanoSight Pro ensures repeatable detection and superior data quality.
