What is cytokine release syndrome?
7 Apr 2024
Cytokine release syndrome (CRS) arises from an excessive activation of both the innate and adaptive immune systems, leading to an overabundance of cytokines, substances capable of influencing other cells. It can be triggered by a variety of factors, such as the presence of certain tumors, infectious diseases, or the administration of therapies including bispecific antibodies or adoptive cell transfer. Delve into the intricate mechanisms underlying CRS and discover an innovative platform from The Jackson Laboratory that is designed to predict CRS.
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The Jackson Laboratory
The Jackson Laboratory is a global leader in preclinical studies and has been driving therapeutic development breakthroughs for over 90 years. With the most innovative preclinical platforms including humanized mice, and services such as dose ranging, toxicity, and efficacy studies, JAX empowers drug developers and researchers worldwide.
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