SelectScience InterviewsDrug Discovery & Development

Humanized mice for therapeutic target validation

11 Sept 2024
Cameron Smith-Craig
Cameron Smith-Craig
Pharma and Applied Sciences Editor
Humanized mice for therapeutic target validation

Dr. Ali Roghanian, Associate Professor at the University of Southampton, explains why better mouse models are needed to bridge the gap between bench to bedside. Exploring existing syngeneic models and how their inherent limitations could be overcome, Dr. Roghanian shares his group’s research using a disseminate model of human breast cancer in humanized mice.

This video was filmed in partnership with The Jackson Laboratory.

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The Jackson Laboratory

The Jackson Laboratory is a global leader in preclinical studies and has been driving therapeutic development breakthroughs for over 90 years. With the most innovative preclinical platforms including humanized mice, and services such as dose ranging, toxicity, and efficacy studies, JAX empowers drug developers and researchers worldwide.

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Humanized mice for therapeutic target validation