UHPLC and HPLC Products & Reviews

The 1260 Infinity III Prime Analytical-Scale LC Purification System is a versatile preparative high-performance liquid chromatography (HPLC) instrument. This system offers the highest functionality and operational convenience for analytical-scale HPLC purification and entry-level quaternary UHPLC at pressures up to 800 bar and for flow rates up to 5 mL/min.

The 1260 Infinity III Prime Bio Analytical-Scale LC Purification System is a versatile preparative high-/ultrahigh-perfomance liquid chromatography (HPLC/UHPLC) system for bioseparations. The system offers outstanding functionality and operational convenience for bioanalytical HPLC and entry-level quaternary bio UHPLC at pressures up to 800 bar and flow rates up to 5 mL/min.

The 1260 Infinity III Bio-Inert Analytical-Scale LC Purification System is a dedicated solution for purifying large biomolecules in biological samples, including monoclonal antibodies and proteins.

The 1290 Infinity III Bio Analytical-Scale LC Purification System is an ultrahigh-performance liquid chromatography (UHPLC) system, configurable with a binary or quaternary pump and consisting of biocompatible material for use in biopharma (such as for critical quality attributes).

Agilent NISTmAb is a reference mAb standard that is intended for system suitability testing, establishing method, instrument, or site-to-site variability, and troubleshooting mAb CQA workflows.

Designed to withstand 100% aqueous conditions and increased retention for polar molecules, InfinityLab Poroshell 120 Aq-C18 columns are the modern and reliable choice for HPLC and UHPLC separations. Now master your polar molecules, especially under water.  

100Å pore size, high ligand density;  available in 1.0, 2.0,  3.0, 4.6 and 10 mm ids;  30 - 250 mm lengths. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% faster…

The 1290 Infinity III Evaporative Light Scattering Detector (ELSD) is ideal for reproducible, sensitve detection of both volatile and nonvolatile compounds that cannot be detected by UV. A unique peltier cooled evaporator coupled with an original gas flow design allow subambient operation down to 10 °C. This delivers maximum sensitivity for compounds with significant volatility below 30 °C.

200A pore size;  available in 3.0 and 4.6  mm ids, and lengths from 50 - 250 mm. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% faster separations without sacrif…

100Å pore size, high ligand density;  available in 1.0, 2.0, 3.0, 4.0, 4.6 and 10 mm ids;  20 - 250 mm lengths. Pursuit columns are ideal for pharmaceutical applications using LC/MS, from analyzing lead compounds and biological samples in drug discovery, to implementing dependable analysis of raw materials and approved drugs in the QC process.  Build on the large 200A pore size silica, high liquid density delivers up to 40% fa…

Agilent Bio-Monolith HPLC columns provide high resolution and rapid separations of antibodies (IgG, IgM), plasmid DNA, viruses, phages and other macro biomolecules. The product family offers strong cation exchange, strong and weak anion exchange, and Protein A phases.

High Throughput with Lowest Carryover      The Agilent 1290 Infinity LC Injector HTC/HTS is designed specifically to meet the throughput and reliability demands of critical LC/MS applications, offering lowest carryover with dynamic load and wash (DLW) principle. This highly versatile system is optimized for high throughput injections, and perfectly complements the infinitely better speed, resolution and sensitivity of the Agil…

Poroshell 120 columns provide rugged, high resolution separations within the pressure range of any mainstream LC system, making the benefits of sub-2 µm performance available with all existing LCs.Poroshell columns can achieve high resolution and high speed separations on current instruments, and higher resolution and speeds on new high-pressure LC and LC/MS systems. Stable to 600 bar, Poroshell 120 are great for fast UHPLC an…

Developed specifically for using LC coupled with GC-FID to accurately determine hydrocarbons found in mineral oils, which can migrate from packaging into food. • 9-component mix contains non-interfering internal standards as well as both mineral oil saturated hydrocarbon (MOSH) and mineral oil aromatic hydrocarbon (MOAH) markers to correctly cut fractions. • Certified reference material (CRM) manufactured and QC-tested in Re…

With Raptor™ LC columns, Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation.

A Restek® LC guard cartridge in an EXP® direct connect holder is the ultimate in column protection.

The Raptor™ ARC-18 column is made specifically for high-throughput, low–sample prep LC-MS/MS applications. A well-balanced retention profile offers better detection and integration of large, multiclass analyte lists, and steric protection helps this SPP column endure the harsh, low-pH mobile phases needed for mass spec without sacrificing retention or peak quality.

Diluted and DEA-exempt—no need to purchase costly neat materials or make your own standards. Pair with Restek's THC standards to analyze both neutrals and acids in cannabis products by LC. A must for accurate quantification in medical cannabis potency testing and strain ID.

Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC® technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation.

Get more of what you want, and less of what you don't, with Roc™ LC columns from Restek.

Force LC columns are available with Restek's most popular and highly selective Biphenyl and FluoroPhenyl phases, as well as a general-purpose C18.

Force LC columns are available with Restek's most popular and highly selective Biphenyl and FluoroPhenyl phases, as well as a general-purpose C18.

Force LC columns are available with Restek's most popular and highly selective Biphenyl and FluoroPhenyl phases, as well as a general-purpose C18.

Restek's Raptor FluoroPhenyl column offers the ability to run in reversed-phase or HILIC mode for a variety of compounds. It is ideal for increasing sensitivity and sensitivity in LC-MS analyses. 

The culmination of 20+ years in LC, Force performance LC columns are long-lasting and reproducible, even under the stress of UHPLC.