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Scientists rate the latest technologies in the field of engineered antibodies

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Take a look at what other researchers and scientists are saying about cutting-edge technologies in engineered antibodies

19 Mar 2021
Diane Li
Assistant Editor

Editorial article

Engineered Antibodies Top List

The demand for more targeted therapeutic and diagnostic antibodies has stemmed from recent developments in antibody production technology. Our Engineered Antibodies Special Feature highlights optimal antibody selection and application, label-free technology for drug discovery workflows, next-generation antibodies, and more.

As part of this feature, we’ve pulled together a selection of top reviews of the latest technologies to aid your work with engineered antibodies. Read on to discover what other scientists and researchers all over the world are saying about these products and how they could benefit your research.

1. Shailendra Kumar at Sterogene Bioseparations uses the Octet RED96e by Sartorius Group for determining binding constants, antibody discovery, and vaccine research:

Shailendra Kumar Review

2. Faraz Harsini at Xbiotech shares his opinion on the OctetRed384 by Sartorius Group:

Faraz Harsini

3. Sankalp Gupta at Sanofi uses the Octet HTX by Sartorius Group for high-throughput antibody characterization and small molecule analysis:

Sankalp Gupta

4. Catherine Langford, from University of Alabama, Birmingham, uses the CD133 antibody by Biorbyt, and here is what she has to say:

Catherine Langford

 

5. Aina Anthi at Mabtech AB uses the Octet Red384 by Sartorius Group for optimized selection of new antibody-producing cells:

 

Aina_Anthi

Find more resources on the Engineered Antibodies Special Feature page >>

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Protein QuantificationThe detection and quantification of proteins in a sample is vital across life sciences, pharmaceutical research and clinical diagnostics, and a variety of equipment is available to scientists to simplify the workflow. Proteins of interest can be easily labeled and detected on light-based detection instruments. Immunoassay kits allow you to identify a specific protein of interest and protein detection beads or antibody microarrays allow you to identify multiple specific proteins at once. Protein interactions and enzyme activity can also be monitored with protein-protein interaction assays. Additionally, the biophysical characterization of proteins is made easy with biokinetic analyzers. Find the best protein detection and quantification products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Therapeutic AntibodiesTherapeutic antibodies are antibodies engineered for use in treating diseases. They can be designed to target specific antigens, blocking harmful interactions or modulating immune responses. Therapeutic antibodies are critical in treating conditions like cancer, autoimmune disorders, and infectious diseases. Explore the best therapeutic antibody products in our peer-reviewed product directory; compare options, check reviews, and get pricing directly from manufacturers.BiotherapeuticsBiotherapeutics are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or in <i>in vivo</i> diagnostics. The most well-known example of a biotherapeutic product, and the first to be approved for therapeutic use, was recombinant human insulin.TherapeuticsTherapeutics are treatments designed to alleviate or cure diseases. These include pharmaceuticals, biologics, and gene therapies, which work by targeting specific disease mechanisms. Advances in personalized medicine and biologics offer new hope for patients with conditions that were previously difficult to treat. Browse our peer-reviewed product directory to find therapeutic solutions for various diseases; compare products, check user reviews, and get pricing directly from manufacturers.ReviewsEngineered AntibodiesEngineered antibodies are modified to enhance specificity, stability, and functionality for therapeutic and diagnostic applications. These antibodies are central to immunotherapy and biomarker detection. Compare engineered antibody solutions in our directory to find top products and reviews.Protein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.

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