Octet® R8 BLI System
Superior quantitation and kinetics performance with increased assay flexibility and cost efficiency.
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Great Equipment, takes minimum space!
Bio Molecular Interaction Analysis and Affinity Characterization
Hi, R8 is a great Equipment!, Its very precise and user friendly. This is our second product of the same make. As service providers, the value we generate for the customers is incredible. Most of our customers are very happy with service we provide, and we could not have done without Octet Red96/R8. It's worth investing for long term usage!
Review Date: 17 Apr 2025 | Sartorius Group
BLI makes kinetic characterization and quantitation easy!
Kinetics & quantitation
Octet R8 is a great equipment for any lab which would like to test their samples for binding, do kinetic characterization and sample quantitation. It is quite fast and informative (compared to techniques such as ELISA), but it is costlier.
Review Date: 13 May 2024 | Sartorius Group
The 8-channel system - Octet® R8 - offers an advanced fluidics-free approach to protein characterization. The independent biosensors allow analysis of single or up to eight channels, enabling flexibility in sample throughput based on need. The Octet system performs quantitation of 96 samples in 32 minutes and kinetic screening of 64 samples in 1.5 hours.
The system utilizes Bio-Layer Interferometry (BLI) technology. The real-time technique enables direct detection of specific proteins and other biomolecules — even in complex mixtures like cell culture supernatants and lysates and low concentration environments.
Furthermore, the label-free technology gathers physiologically relevant data quickly, proving to be a cost-effective method.
Key Benefits:
- Large dynamic range for comfortable titer determination Versatile kinetic analysis from small molecules (150 Da) to cells
- Temperature Control (15–40°C) Evaporation protection for long off-rate measurements
- Full post-analysis sample recovery Low maintenance and operational costs
- Ready for GxP regulated environments
Popular industrial applications include expression screening, on- and off-rate screening, epitope binning, cell line development and bioprocess optimization.
The Octet® R8 system is widely used in analytical core labs for protein structure/function studies and small molecule screening campaigns. The system has been developed to operate reliably in a regulated environment. Sartorius offers 21 CFR Part 11 software and a full line of GxP products and services as part of the Octet® R8 GxP Package.
Enhanced BLI analytics with new heights of sensitivity
Explore Sartorius’ most advanced biolayer interferometry (BLI) solution, designed for high-throughput, real-time biomolecular interaction analysis. The Octet® R8e delivers best-in-class sensitivity, enabling accurate detection of low molecular weight and low-abundance analytes. With features like 384-well plate compatibility, reduced sample volume (as low as 40 µL), extended unattended runtime (up to 16 hours), and intuitive software for streamlined workflows, this system empowers researchers to achieve reliable results faster and more efficiently. Ideal for applications across drug discovery, biologics development, and manufacturing.
Accelerate assay development and reduce cycle times for AAV quantification in complex biological samples
Assessing AAV vector quality in gene therapy manufacturing is crucial, but the current gold standard, serotype-specific ELISA, has its drawbacks — time-consuming and prone to matrix effects. In this webinar, Dr. Yoann Saucereau from ExcellGene reveals how a label-free approach not only cut down on complexities in biological matrices but also enabled a quick, routine method. Now, ExcellGene effortlessly analyzes up to 96 samples in under 30 minutes for efficient AAV platform development.
Key learning objectives
- Explore how suitable QC workflows are established in AAV development and manufacturing
- Discover the critical role of assay design and development to determine correct binding kinetics, affinity values or analyte concentrations
- Consider the optimization and evaluation of an AAV titer assay in comparison to Octet® AAVX Biosensors
Who should attend?
- Lab researchers
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
Revolutionize care with pioneering bispecific antibody therapy
Jiseon Kim, Senior Scientist at ProGen, explores the transformative potential of a bispecific antibody-based drug to lay the foundation for improved healthcare quality
