Octet® RH16 BLI System
High throughput label-free performance.
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The system provides analytical performance similar to the 8- channel Octet® R8 system, but with higher levels of throughput, speed, and flexibility. The high detection sensitivity and impressive throughput of Octet® RH16 system has made it a favorite for small molecule library screening and analysis of large cross-competition binding matrices. Kinetic analysis including association and dissociation of biomolecules can be performed on up to 384 samples in one 384-well microplate.
Fully automated workflows can be realized due to integrated robotic solutions, extending the unattended run time of the system. Target ligands can be batch immobilized onto biosensors and returned to the biosensor tray for re-use in future experiments, thus extending the number of uses for each biosensor, preserving valuable ligand, and maximizing flexibility in experimental design.
Key benefits:
- Sensitivity - Detection of low molecular weight molecules (≥ 150 Da)
- High throughput - 16-well simultaneous sampling in 384-well and 96-well formats
- Flexibility - Two plate locations maximize throughput and improve workflow
- Unattended operation - Automation friendliness allows multiple-plate assays in one run
- User-friendliness - Advanced software offers greater versatility in experimental design and data analysis
Accelerate assay development and reduce cycle times for AAV quantification in complex biological samples
Assessing AAV vector quality in gene therapy manufacturing is crucial, but the current gold standard, serotype-specific ELISA, has its drawbacks — time-consuming and prone to matrix effects. In this webinar, Dr. Yoann Saucereau from ExcellGene reveals how a label-free approach not only cut down on complexities in biological matrices but also enabled a quick, routine method. Now, ExcellGene effortlessly analyzes up to 96 samples in under 30 minutes for efficient AAV platform development.
Key learning objectives
- Explore how suitable QC workflows are established in AAV development and manufacturing
- Discover the critical role of assay design and development to determine correct binding kinetics, affinity values or analyte concentrations
- Consider the optimization and evaluation of an AAV titer assay in comparison to Octet® AAVX Biosensors
Who should attend?
- Lab researchers
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
