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7 lab products advancing drug discovery

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Take a look at what other researchers and scientists are saying about cutting-edge technologies in drug discovery

27 Apr 2021
Edward Carter
Publishing / Media

Editorial article

Here at SelectScience, our goal has always been to provide scientists worldwide with the information they need to make the best purchasing decisions to advance their work. But we couldn't do that without the support and input of our vast community of reviewers. Here, as part of our new Advances in Drug Discovery Special Feature, we’ve collated a selection of our favorite reviews of the technologies involved in drug discovery. Find out why these products have been recommended by your peers and see how they could help improve your own workflows.

1. Justin Jeong, from Genentech, shares his opinion on the Agilent 1290 Infinity II Bio LC System:

2. Grace Lee, at University of Utah School of Medicine, uses INTEGRA’S ASSIST PLUS to analyze proteins from tissue samples:

3. David McChesney, at University of New Mexico College of Pharmacy, uses the NanoSight NS3000. Here is what he had to say:

4. Satish John, from Anant Pharmaceuticals, shares his opinion on the Lyovapor™ L-200 by Buchi:

5. Yasushi Sakaguchi, at DKSH Japan, uses the FlowCam® 8000 from Yokogawa Fluid Imaging Technologies to analyze protein aggregates in biologics:

6. J H, from EMD Serono, shares their opinion on Transcreener® ADP² Kinase Assays by BellBrook Labs:

7. Joyce James, at Lyric Pharmaceuticals, uses LGC’s Small Molecule Bioanalysis Service to analyze small molecules in plasma for pharmacokinetics and biomarkers in pharmacodynamics:

Explore more drug discovery resources in our Advances in Drug Discovery Special Feature>>

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Agilent 1290 Infinity II Bio LC System

Agilent Technologies

The 1290 Infinity II Bio LC System is a UHPLC, binary or quaternary ,- consisting of biocompatible material for use in biopharma (e.g., critical quality attributes) and other applications utilizing high salt and extreme pH conditions. Biocompatibility ensures the integrity of your biomolecules and robustness of the system.

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FlowCam 8000

Yokogawa Fluid Imaging Technologies, Inc

Through its exceptional image quality and the widest size range available, FlowCam® 8000 represents state-of-the-art particle imaging technology. Analyze thousands of particles in less than a minute and comprehensively characterize the size, count, morphology, and identity of subvisible and visible particulates in their native solvent.

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Combinatorial ChemistryCombinatorial chemistry, also known as combichem, is a technique used in drug discovery to create libraries of structurally related compounds. A library is generated by synthesis with a chemical reactor system or by computer-based modeling of compound combinations. When undertaking combinatorial chemistry consider reagents, buffers, resins and standards.Lab-on-a-ChipLab-on-a-chip (LOC) technology uses microfluidic chips, such as microarrays, to perform biochemical assays on a small scale. Benefits of lab-on-a-chip include the small volume of sample required as well as the speed of analysis. In selecting lab-on-a-chip devices consider the assay, cost, reliability, sensitivity and signal to noise ratio.Compound LibrariesCompound libraries, or chemical libraries, are used in drug discovery for the identification of potential therapeutics compounds. Used in conjunction with high-throughput screening, the libraries of stored compounds are often generated for specific purposes as a drug target or disease model. Cheminformatics are commonly used when designing a compound library and software can be used to analyze the screening process.  Biopharmaceutical AdvancesBiopharmaceutical advances follow the development of pharmaceuticals derived from biotechnology, also known as biotechnology medicines. Biopharmaceuticals may be produced from cell lines, plants, or microbial cells. Important considerations of biopharmaceutical use include application, cost, production process and purification.Plate ProcessingAutomated plate processing is used in microplate technologies for high-throughput, speed and efficiency. Plate processing systems include microplate handlers for moving plates, heat sealers, stackers and carousels for storage, retrieval and delivery, microplate washers and piercers. Useful features of plate processors include walk-away automation, compatibility and easy integration with microplate systems.GC-MS GC-MS (gas chromatography-mass spectrometry) instruments and equipment are used to separate, quantify and identify mixtures of small and volatile compounds, such as polycyclic aromatics, fatty acids and alcohols. Often used in drug detection, forensic investigation and environmental analysis for pesticides and contaminants, GC-MS is a powerful addition to your lab’s analytical capabilities. GC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzers can give greater sensitivity and resolution to your analysis. Find the best GC-MS instruments and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunoassayImmunoassays are laboratory tests that utilize antibody-antigen interactions to detect specific substances. They are widely used in diagnostics for detecting diseases, drug testing, and environmental monitoring. These assays offer rapid, sensitive, and precise detection of biomarkers, making them invaluable in clinical and research labs. Browse our peer-reviewed product directory to compare immunoassay systems, read user reviews, and get pricing directly from manufacturers.Drug DiscoveryDrug discovery is the process of identifying potential new medications, involving stages such as target identification, compound screening, and preclinical development. It relies on cutting-edge technologies like high-throughput screening, artificial intelligence, and molecular modeling to accelerate the identification of drug candidates. Drug discovery plays a pivotal role in developing new therapies for diseases ranging from cancer to rare genetic disorders. Browse our peer-reviewed product directory to find the latest drug discovery technologies, compare options, check customer feedback, and get pricing directly from manufacturers.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.Drug DevelopmentDrug development refers to the process of bringing a new drug to market.Protein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.

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7 lab products advancing drug discovery