Agilent 1290 Infinity II Bio LC System
The 1290 Infinity II Bio LC System is a UHPLC, binary or quaternary ,- consisting of biocompatible material for use in biopharma (e.g., critical quality attributes) and other applications utilizing high salt and extreme pH conditions. Biocompatibility ensures the integrity of your biomolecules and robustness of the system.
Agilent 1290 Infinity II Bio LC System
ACT Label awarded to the 1290 Infinity II LC System
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The 1290 Infinity II Bio LC System is a UHPLC, binary or quaternary ,- consisting of biocompatible material for use in biopharma (e.g., critical quality attributes) and other applications utilizing high salt and extreme pH conditions. Biocompatibility ensures the integrity of your biomolecules and robustness of the system.
Based on proven 1290 Infinity II LC technology, the system offers easy method transfer, also from legacy instrumentation, and saves time and effort spent on training. It provides highest resolution and lowest dispersion at pressures up to 1300 bar. A variety of bio flow cells are available for sensitive UV detection.
Features
- Biocompatible solvent and sample flow path ensure integrity of biomolecules and minimize unwanted surface interaction
- Different bio accessories include a range of bio heat exchangers, bio capillary kits, bio loops, and analytical heads to cover all the different application needs for instrument versatility and efficiency
- Flexibility for all applications - through wide power, temperature, an automatically scalable injection range, and gradient options (binary and quaternary solvent mixing)
- Lowest delay volume throughout the system enables highest chromatographic resolution and lowest dispersion
- High salt tolerance and wide pH range offer enhanced flexibility and robustness for increased instrument uptime
- Based on the proven 1290 Infinity II technology for easy method transfer, also from legacy instrumentation, and less training effort
- Shallow microplate drawers take a maximum load of 6,144 samples for unmatched sample capacity
- Power range combines ultrahigh pressure up to 1300 bar and high analytical flow rates up to 5 mL/min for maximum UHPLC performance
- A wide range of sensitive optical detection capabilities with various flow cells for VWD, DAD, FLD, Bio MDS, or LC/MS detection for highest adaptability
Separation of organic acids on an Agilent InfinityLab Poroshell 120 Aq-C18 column
In this application note, an InfinityLab Poroshell 120 Aq-C18 column is used for the analysis of organic acids under a highly aqueous mobile phase. Two mobile-phase additives were investigated, and the method was optimized separately. Organic acids are an important group of components in many food samples, including fruit drinks, wine, and other aqueous samples. Download this free application note to discover more, including the results of these analyses.
From Start to Finish: How Agilent Can Support Better Decisions in IVT mRNA-Based Biopharmaceutical Analysis
Jan 21st 2025 - 16:00 GMT / 17:00 CET / 11:00 EST / 8:00 PST
Development and production of IVT mRNA vaccines require measurements of Critical Quality Attributes (CQAs), such as identity, purity, quality, and quantity. Orthogonal methods developed for such purposes are outlined in the USP guidelines for mRNA vaccines.
Agilent Technologies provides many analytical solutions that are used by leading pharmaceutical companies in early-stage drug development through production quality control (QC) and final product release. These systems help users save time and money with optimized workflows, streamlined processes, and fast time-to-results.
Whitney Pike, M.Sc, Application Scientist and Dr. Sonja Schneider, Manager, Application Development, Agilent Technologies, will discuss how automated electrophoresis and LC/MS systems solutions from Agilent provide reliable insights for IVT mRNA workflows at many steps, from QC of the initial plasmid DNA, throughout the IVT process, to the finished mRNA drug product.
Key learning objectives
- Explore QC throughout the entire IVT mRNA workflow, including data from various nucleic acids and LNP analyses
- Discover how Agilent instruments/technologies, such as the Fragment Analyzer and LC/MS systems, can be used for different CQAs
- Learn how Agilent is working together with its partners to provide reliable insights for all aspects of the IVT mRNA workflow
Who should attend?
- Researchers, lab managers, lab directors, QA/QC managers performing IVT mRNA analysis in biotherapeutics research and production
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
For Research Use Only. Not for use in diagnostic procedures. PR7001-2498
