Product DemonstrationsLife Sciences

The oKtopure Automated DNA Extraction Platform from LGC Genomics

9 Oct 2013

The oKtopure form LGC Genomics is a fully automated DNA extraction instrument that enables a new level of high throughput processing and significant cost savings. Watch this video to see the oKtopure in action.

About the company

LGC Diagnostics and Genomics - Rapid Genomics Genotyping Solutions logo

LGC Diagnostics and Genomics - Rapid Genomics Genotyping Solutions

Biosearch Technologies is the comprehensive genomics portfolio from LGC, providing products and services for genomic analysis that support mission critical applications for global customers in agrigenomics and human healthcare.

The portfolio offers integrated tools and technologies to accelerate sample preparation, amplification, cloning and expression, next generation sequencing (NGS), custom oligonucleotide synthesis, nucleic acid chemistry reagents, and oligo therapeutics.

Whether through sbeadex™ extraction, oligos and reagents (KASP™, BHQplus™ probes, BHQ™ Probe Master Mix), or proprietary sample prep and PCR instrumentation (oKtopure™, SNPline, Nexar™, and IntelliQube™), we enable our customers from discovery to production-scale testing.

Biosearch Technologies is a leader in the agricultural genomics market and is increasingly adopted by researchers, with over 2000 scientific papers citing KASP assays. Key applications include validation and screening of newly discovered SNPs in Marker-Assisted Selection and Marker-Assisted Breeding programmes for both plants and livestock.

Globally, our cGMP manufacturing and ISO 13485-compliant facilities support supply chain continuity, complementing our customers’ product development pipelines through our robust research grade and cGMP oligonucleotide manufacturing that achieves consistent scale up. For molecular diagnostics, Biosearch Technologies has proven expertise in NGS, isothermal, qPCR-based applications where our tools and technologies such as BHQ probes and proprietary PCR platforms are frequently used in LDTs, ASRs and in vitro diagnostics. Through our recently acquired Lucigen portfolio, we also offer custom and bulk enzymes and buffers as critical components for molecular diagnostics.

Sales offices are located in China, Germany, Singapore, UK, and US. Sales representatives are available throughout Europe, Latin America, and Asia Pacific, with distributors in other key territories. Visit www.biosearchtech.com.

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oKtopure™ - Automated nucleic extraction platform

LGC Diagnostics and Genomics - Rapid Genomics Genotyping Solutions

The oKtopure™ is a fully automated nucleic acid extraction instrument that enables a new level of high-throughput processing and significant cost savings. This platform combines standardised high-throughput DNA or RNA extraction from a variety of sample types with the proprietary sbeadex™ magentic bead based extraction chemistry. The oKtopure is part of our on-going programme to provide customers with high productivity solutions, first developed and optimised for use within our service labs, where every day we deliver Extraction, Sequencing and Genotyping services. Key to the delivery of consistently high quality and high yield DNA preparations from the oKtopure is its ability to bind and hold the magnetic beads, and hence the DNA in place whilst transferring the buffers required for washing, binding and elution steps. The final aqueous wash used in the sbeadex extraction protocols enables the delivery of nucleic preparations ideal for downstream applications such as SNP genotyping, NGS and Sanger sequencing. Features: High throughput - capable of processing eight 96-well plates (768 samples) in approximately one-and-a-half hours Robust tip washing system reduces consumable costs by 50% or more Preloaded methods for different sample types – fully customizable Extraction expertise and support from scientists who use the instrument daily and have been carrying out high throughput extractions since 1996!

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