Revolutionizing liquid handling in life sciences
11 Feb 2026
The life sciences field continues to advance rapidly, driven by new tools that enhance accuracy and efficiency at the bench. Discover how NANOlab™ from BioDot is supporting this progress with innovative liquid‑handling technologies designed to deliver precise, low‑volume dispensing while maintaining high data quality and cost‑effective operation. Its disposable tip formats help protect sample integrity by minimizing cross‑contamination, and the integration of advanced robotics with intuitive software enables fast, reliable dispensing across a wide range of formats and custom layouts. Together, these developments are helping laboratories streamline workflows and achieve more consistent, reproducible results.
About the company

BioDot Inc.
BioDot aims to become the principle supplier of sub-microliter dispense systems (for the manufacture of micro-array and microfluidic devices) to Molecular Diagnostics, Theranostics and other emerging markets. This is driven by on-going technology development programs delivering Dispensing Innovation products like BioJet Plus. This unique non-contact nanoliter dispenser delivers genuine on the fly deposition of small drop volumes for high throughput production of Biosensors, BioChips and Protein/Cell arrays.
BioDot is already established as world leader in the supply of equipment and technology for the development and manufacture of membrane Rapid Diagnostic Tests and Biosensors.
BioDot enables, inspires, and educates scientists to commercialize their ideas from R&D through to manufactured product.
Video transcript
Show transcript
[00:00] Welcome to today's demonstration of the ImageXpress HCS.ai High-Content Screening System. I'm Dr. Sarah Chen, and I'll be your guide through this cutting-edge technology.
[00:15] The ImageXpress HCS.ai represents a significant leap forward in high-content screening capabilities. What sets this system apart is its combination of high-definition imaging with AI-powered analysis
[00:45] Let's start with the hardware. As you can see here, the system features a completely redesigned optical path that delivers twice the acquisition speed of previous generation systems. This means you can process more plates in less time without sacrificing image quality.
[01:20] The imaging quality is truly remarkable. We're achieving brighter, clearer images with improved signal-to-background ratios across both brightfield and fluorescent imaging modes. The system supports confocal imaging with optional automated water immersion optics.
[02:00] Now, let me show you the software integration. The system seamlessly combines MetaXpress Acquire for image capture with IN Carta Image Analysis for AI-enhanced processing. This integration enables fast, automated, and flexible data processing.
[02:45] One of the most exciting features is the system's ability to handle complex 3D biological models. Here you can see high-resolution imaging of organoid cultures. The AI-powered quantification allows for accurate phenotypic profiling and drug-response analysis.
[03:30] The modular design is another key advantage. As your laboratory's needs evolve, you can easily add new imaging modes, optical options, or automation tools. This upgrade-friendly architecture protects your investment.
[04:15] Let me demonstrate the workflow. From sample preparation through image acquisition to data analysis, every step has been optimized for efficiency and ease of use. The intuitive interface means new users can get up to speed quickly.
[05:00] The system's throughput capabilities are impressive. We're seeing significant improvements in plate processing times, which directly translates to higher productivity in your high-throughput screening applications.
[05:45] For those working with advanced assay formats, the system provides robust support for both 2D and 3D cell assays. Whether you're doing cellular research, drug discovery, or phenotypic screening, the HCS.ai delivers the depth of insight you need.
[06:30] Thank you for joining me today. If you have any questions about the ImageXpress HCS.ai High-Content Screening System, please don't hesitate to reach out to our team. We're here to help you achieve your research goals.
What does this video cover?

Topics covered in this video
- 02:47 -Rheumatic Diseases Overview
- 10:03 - Biomarkers & Calprotectin
- 18:50 - Still Disease Guidelines
- 24:23 - Turbidimetric Assay Study
- 27:55 - COMPASS Cohort Study
FAQs
What is the ImageXpress HCS.ai High‑Content Screening System?
It is an advanced imaging platform designed for high‑content screening across 2D and 3D assays, providing high‑definition data and flexible workflows for life science research.
How does the system improve imaging quality?
It enhances image clarity with improved signal‑to‑background performance, multiple imaging modes (brightfield, widefield, confocal), and optional water immersion optics for increased sensitivity.
What software tools are included?
Image acquisition is handled by MetaXpress® Acquire, while AI‑powered image segmentation and analysis are performed using IN Carta® Image Analysis software.







