Simulated Moving Bed Chromatography (SMBC) for Continuous Purification of Xylitol
11 Jan 2018
Simulated moving bed chromatography (SMBC) was applied for the purification of xylitol from fermentation mash of a fed batch culture, enabling nearly 100 % purity and recovery. This tehnique allows for large-scale purification of xylitol from the biological xylose-xylitol conversion process.
About the company

KNAUER Wissenschaftliche Geräte GmbH
We separate molecules and unite people.
Based in Berlin, KNAUER is a medium-sized, owner-managed company that has been serving the sciences since 1962. We develop and manufacture scientific instruments of superior quality for liquid chromatography systems and components, including:
- Analytical HPLC / UHPLC
- Preparative HPLC
- Fast protein liquid chromatography (FPLC)
- Multi-Column Chromatography / Simulated moving bed (SMB)
- Osmometry
With 135 employees, we are an established manufacturer of HPLC systems and components. Our valves, pumps, detectors, and other components are used for many separation processes outside of HPLC and are popular with customers who want custom solutions (OEM). KNAUER is an ideal partner for those who want more than standard solutions can provide. Osmometers for the determination of molality were the first products of the family business and the cornerstone of its success. KNAUER continues to develop and manufacture industry-leading osmometers.
Furthermore, the KNAUER Academy offers courses on HPLC and application development.
We support technological advancement today and in the future.








