Exploring a novel target in therapeutic chemistry with CETSA
27 Nov 2024Jonathan Ellery, Director of Biology at Sitryx, shares his experience of using CETSA® from Pelago Bioscience, to investigate a new target with established chemistry. CETSA proved useful in addressing concerns about the compound's effectiveness in tissues by confirming the compound's binding and stabilization of the target, while providing insights on target engagement.
About the company
Pelago Bioscience
Pelago Bioscience was founded in 2013 with the aim to develop the patented Cellular Thermal Shift Assay (CETSA®) for maximum utility and customer value in drug discovery and diagnostics. Today, Pelago Bioscience is a Drug Discovery Research Partner supporting preclinical drug discovery and development. Pelago offer a range of services, from confirming target engagement to strengthening target validation and understanding the mechanism of action of your compounds. The approach is designed to help you make better decisions faster.
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