Explore how CETSA achieves relevant target engagement
12 Apr 2023
In this video, Pelago describes how the CETSA® is a well-proven, best-in-class technology used to assess cellular protein-ligand binding. CETSA can be applied throughout all steps of the drug discovery value chain. Because neither the ligand nor the protein is modified, CETSA provides reliable measurements of target engagement in authentic cellular environments and under actual physiological conditions. In this way, biologically relevant values can be obtained from any type of cellular matrix; cell lines, animal tissue, or patient samples, and helps you explore, discover, and confirm drug candidates faster.
About the company
Pelago Bioscience
Pelago Bioscience was founded in 2013 with the aim to develop the patented Cellular Thermal Shift Assay (CETSA®) for maximum utility and customer value in drug discovery and diagnostics. Today, Pelago Bioscience is a Drug Discovery Research Partner supporting preclinical drug discovery and development. Pelago offer a range of services, from confirming target engagement to strengthening target validation and understanding the mechanism of action of your compounds. The approach is designed to help you make better decisions faster.
