Detecting Bioterrorism Threats Using an Enzyme-Linked Oligonucleotide Assay Approach
16 Jan 2017
Ioanis Katakis and Ciara K. O’Sullivan, Universitat Rovira i Virgili’s Interfibio Research Group, describe how they developed an enzyme-linked oligonucleotide assay (ELONA) approach to detect potential biowarfare agents such as Yersinia pestis. Their work provides proof of concept for applying RPA in a heterogeneous format, with one primer immobilized onto a solid surface.
About the company
TwistDx
TwistDx designs and manufactures Recombinase Polymerase Amplification or RPA, a multiplexable, isothermal DNA/RNA amplification and detection technology that works amazingly fast without the need of a thermocycler. RPA is a portable alternative to PCR and is ideally suited to point-of-use molecular assays for digital, microfluidics, agriculture, veterinary and biodefense applications.
