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Cell line engineering with CRISPR-Cas9: Genetic considerations

20 Oct 2020
Cell line engineering with CRISPR-Cas9: Genetic considerations

Kevin Hemphill, R&D Scientist at Horizon Discovery, discusses the genetic considerations you should think about prior to embarking on generating a cell line using crispr including gene essentiallity, investigating copy number and the pseudogene burden of your gene of interest as well as how to deal with genes that have multiple transcripts.

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