Breaking barriers: Unravelling cell heterogeneity with single-cell proteomics
18 Jun 2023
The Cell Diversity Lab at the Technical University of Denmark is utilizing mass spectrometry-based proteomics to unravel fundamental biological concepts controlling heterogeneity within complex biological systems.
In this video, Prof. Erwin Schoof, Associate Professor, Cell Diversity Lab, Technical University of Denmark, explains how the Thermo Scientific™ Orbitrap™ Astral™ mass spectrometer is revolutionizing single-cell proteomics, enabling the Cell Diversity Lab to characterize low abundant proteins such as transcription factors, kinases, and epigenetic regulators which were previously undetectable by mass spectrometry. Prof. Schoof also discusses his thoughts on the future of single-cell proteomics and the ever-increasing role he believes multiplex data independent acquisition will play in improving the throughput of single-cell analysis.
This video was filmed at ASMS 2023.
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Thermo Scientific Orbitrap Astral mass spectrometer
Thermo Fisher ScientificThe Thermo Scientific™ Orbitrap™ Astral™ mass spectrometer is powered by the synergy of a high-resolution quadrupole mass filter, Thermo Scientific™ Orbitrap™ analyzer and novel Thermo Scientific™ Astral™ analyzer to achieve unsurpassed performance and experimental flexibility. The combination of the three mass analyzers enables the rapid acquisition of exceptional quality high resolution accurate mass (HRAM) full scan and MS/MS spectra with high sensit
