Transfer of an Itaconate Production Process in Ustilago Maydis to the BioFlo 120 Bioprocess Control Station
19 Jan 2018Itaconate, an unsaturated dicarboxylic acid derivate of cis-aconitate, is an important compound in many industries, including the production of pharmaceuticals, adhesives, and biofuels. This application note refers to the use of the BioFlo 120 bioprocess control system in the fed-batch cultivation of genetically engineered Ustilago maydis fungus for industry-relevant itaconate manufacture, by researchers at the RWTH Aachen.
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Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.BioprocessingBioprocessing is the use of biological systems for the conversion of raw materials to desired products. This includes the research, development and manufacturing stages of production and can refer to food processing, small-molecule pharmaceutical manufacture, production of recombinant protein therapeutics, or the generation of renewable energy.Cell GrowthCell growth refers to the process by which cells increase in size and number. It is essential for tissue development, wound healing, and cancer research. Understanding and controlling cell growth is a fundamental part of cell biology and regenerative medicine. Browse our peer-reviewed product directory to find the best tools for studying cell growth, compare products, check reviews, and get pricing directly from manufacturers.Cell CultureCell culture involves growing cells under controlled conditions, typically outside of their natural environment, to study cellular behavior, drug response, and disease models. Cell culture is crucial in biotechnology and biomedical research. Explore cell culture products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.