Choosing the right ITC binding experiment
23 Jan 2026Isothermal titration calorimetry (ITC) can be used to obtain a complete understanding of the driving forces leading to a binding interaction. Explore three methods using ITC and learn how each are beneficial depending on what stage the technique is used in the workflow. Plus, discover the power of enthalpy screening and continuous titration to reduce experimental time.
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TitrationTitration is an analytical technique for determining substance concentration in a solution. For titration consider a manual or automated system, volumetric or coulometric reagent addition and indication by a potentiometer, spectrometer, turbidometer or by the Karl Fischer method. Other features of titration to consider include burettes, reagents, concentration range, reaction time and autosamplers.High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.isothermal titration calorimetry