Reveal Human-Growth Patterns in Transcriptomic Data

13 Dec 2018

Dr. Stevens is doing both bench studies and in silico studies on a range of omics datasets derived primarily from blood samples throughout human childhood. The datasets include transcriptomic data – which measures RNA and microarray RNA sequencing, looks at the integration of genetic data and other omics data (such as proteomics and phosphor proteomic data). These datasets are used to study both normal childhood growth and growth with various impairments. For example, at short stature, where there is a growth hormone deficiency, and chromosomal syndromes, for example Turner syndrome, where girls are often treated with growth hormones. Dr. Stevens has experienced that a fundamental problem is that if you’re running a project and realize you need statistics expertise you find statisticians but they don’t always understand the biology.

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ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.SequencingSequencing refers to determining the order of nucleotides in a DNA or RNA molecule. This process is essential in genomics, diagnostics, and evolutionary biology. Techniques like next-generation sequencing (NGS) and Sanger sequencing provide high-throughput and precise data for analyzing genomes and transcriptomes. Browse our peer-reviewed product directory to find the best sequencing tools and reagents, compare products, check reviews, and get pricing directly from manufacturers.TranscriptomicsBig DataBig data is described as data sets that are extremely large and complex, and can be challenging to process.