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Quality control and quality assurance in the food industry

SelectScience
26 Jan 2023

The production of foods and beverages for human and animal consumption is governed by a whole host of regulatory agencies across the globe and also by guidelines on Good Manufacturing Practice (GMP).

In this eBook, we consider the suite of chromatography solutions from Thermo Fisher Scientific coupled with their various MS technologies (and other add-ons) through case studies demonstrating their application in QC testing of a wide range of food and beverage products.

Understand how these analytical methods overcome problems arising in traditional approaches, such as sample matrix interference or the need for pre-processing (e.g. derivatization), thereby enabling the high-resolution separation of complex samples at greater speed followed by high-sensitivity detection.

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Dionex™ ICS-5000+ Capillary HPIC™ System

Thermo Fisher Scientific

Built on our top-of-the-line IC platform, this system provides the high performance, convenience, and flexibility of the Thermo Scientific™ Dionex™ ICS-5000+ HPIC System optimized for capillary flow rates. Customize a dual capillary system to run two different analyses concurrently on a single sample, or analyze two samples in parallel. Alternately, run the same analysis on both channels to double throughput. For advanced IC x IC (2D IC) applications and sample pretreatment, combine a capillary channel with a 2- or 4-mm format channel to build a hybrid system. High Pressure, High Performance Fast, sensitive separations without sacrificing resolution—up to two times faster with Fast IC columns Outstanding resolution using columns with small-diameter particles, thanks to high-pressure capability Continuous operation at up to 5000 psi when configured as a Reagent-Free™ IC (RFIC™) system Optimized peak resolution with a choice of isocratic and electrolytic gradient separations on each channel Powerful and user-friendly operation via Thermo Scientific™ Dionex™ Chromeleon™ Chromatography Data System Wide variety of chemistries available in Thermo Scientific™ capillary and Fast IC columns Flexible, easy to configure, modular design Time-saving dual system option The Capillary Advantage Always ready with 24/7 uptime and minimal calibration and equilibration time Up to 18 months of continuous operation on one Eluent Generation cartridge Small dead volumes for minimized peak dispersion Reduced eluent disposal costs—only 15mL/day if eluent used for continuous operation at 10µL/min Enhanced ease-of-use with the Dionex IC Cube, capillary consumable cartridges and simple, color-coded connections Flexible support for capillary columns of 0.2–0.6mm I.D. Application Flexibility Choose from a broad variety of Dionex ICS-5000+ modules and related products. See the Dionex ICS-5000+ HPIC System Product Features for a full list. Sample Preparation and Automation Solutions Dionex autosamplers integrate seamlessly with all Dionex ICS-5000+ HPIC systems, providing effortless automation and advanced sample preparation capabilities.

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Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. UV-Visible SpectroscopyUltraviolet-visible (UV-Vis) spectrophotometers are used to measure the interaction of UV and visible light with a sample, including transmission, reflectance & absorbance. The two major instrument classes are single-beam or double-beam spectrophotometers. More specialized equipment includes colorimeters, spectroradiometers and refractometers. Portable and microvolume spectrophotometers are also available. For the modular spectroscopy lab, explore a range of light sources for combination with a spectrograph/spectrometer and optics. Find the best UV-Vis spectroscopy products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Food and Beverage ProcessingFood and Beverage Processing involves the preparation of food products for further analysis. Typical instrumentation includes blanchers, color sorters, cookers, grinders, and refrigeration. These are used to replicate the processes commonly used in the commercial preparation of food and beverages.Food SafetyFood safety describes the prevention of food-borne illnesses. Contamination with a variety of pathogens can be prevented with adequate temperature control, hygiene and labeling. Food samples can be tested using GC/MS, HPLC, SPE, and qPCR to ensure their adherence to regulations.Food TestingFood testing refers to a variety experiments including PCR, mass spectrometry, processing, QuEChERS, analyzing and Kjeldahl.Food QualityFood quality refers to the attributes of food that influence its safety, nutrition, and taste. Monitoring and ensuring food quality are essential in production to meet health regulations and consumer expectations. Techniques like spectroscopy, chromatography, and microbial testing are used to assess food properties and detect contaminants. Browse our peer-reviewed product directory to find food quality testing solutions; compare products, check reviews, and get pricing directly from manufacturers.

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Quality control and quality assurance in the food industry