Macrocycle Library: Macrocyclic Compounds for Challenging Targets
20 Mar 2017The use of synthetic macrocycles is becoming a well-recognized and successful approach for low druggability targets such as antimicrobial, antiviral and protein-protein interaction. Through focusing on solutions to the synthetic challenges the chemists at ChemBridge® have produced a diverse library of over 6,000 macrocycles that are in stock and available for purchase.
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Compound LibrariesCompound libraries, or chemical libraries, are used in drug discovery for the identification of potential therapeutics compounds. Used in conjunction with high-throughput screening, the libraries of stored compounds are often generated for specific purposes as a drug target or disease model. Cheminformatics are commonly used when designing a compound library and software can be used to analyze the screening process. Discovery SoftwareComputational techniques used in both the chemistry and biology aspects of drug discovery, for data acquisition, processing and storage. Software is used for analysis of pathways, target identification, genomics, proteomics, modelling, lead identification, compound analysis and drug modelling among many others. Compound AnalysisCompound analysis is used to discover specific compounds that could be promising candidates for pharmaceutical use. This potential is identified when compounds have the desired effect, such as interaction with a target protein, during high throughput screening.