From shaker to pilot/production bioreactor: How scale-up assist using the BioFlo 720 Bioreactor Control System can help your antibody production workflow
27 May 2021In this application note, Eppendorf demonstrates the cultivation of Chinese Hamster Ovary cells (CHO) using BioBLU Single-Use Vessels and a Thermo Scientific™ HyPerforma™ 50 L SUB, showing that the parameters provided by the new Scale-Up Assist software resulted in similar cell growth and monoclonal antibody (mAb) production yields for all three vessel sizes.
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Bioprocessing / FermentationBioprocessing is the use of biological materials to perform commercial, scientific or medical research processes. Biological materials used include cells, enzymes and organisms. Usually bioprocessing requires a batch or continuous bioreactor such as a fermentor or cell culture system. The advantages of using a reactor include high productivity, easy configuration, adjustable values and automation.BioprocessingBioprocessing is the use of biological systems for the conversion of raw materials to desired products. This includes the research, development and manufacturing stages of production and can refer to food processing, small-molecule pharmaceutical manufacture, production of recombinant protein therapeutics, or the generation of renewable energy.Antibody ProductionAntibody production is essential for a wide range of applications in biochemistry and immunology. Ensuring high-quality monoclonal and polyclonal antibodies are produced is key. Explore antibody production tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.