ResourceDrug Discovery & Development
Assessment of small molecule kinetics and affinity using OneStep Injections in SPR screening
29 Oct 2025This application note explores how OneStep® injections on the Octet® SF3 SPR system revolutionize small molecule and fragment-based drug discovery. By enabling real-time kinetic and affinity analysis from a single injection, OneStep® eliminates the need for serial dilutions and multi-cycle assays, saving time, sample, and cost. Learn how this method delivers high-content data with minimal setup, allowing researchers to screen hundreds of compounds rapidly and confidently.
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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Biophysical CharacterizationBinding Kinetics