Unveiling the drivers of inflammatory bowel disease

27 Jan 2026

The rapidly evolving landscape of preclinical inflammatory bowel disease (IBD) research demands innovative approaches to unravel the complex mechanisms underlying the disease. This resource shows how Inotiv is applying a multidisciplinary approach to characterizing preclinical IBD models, using the adoptive T cell transfer (TCT) model as an example. It also covers the use of digital pathology, AI-driven image analysis, global proteomic and spatial transcriptomic analysis, to further investigate the mechanisms behind the disease phenotypes and its therapeutic responses.

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ProteomicsProteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.Artificial Intelligence / Machine LearningArtificial intelligence (AI) and machine learning (ML) are transformative technologies used to analyze complex data, identify patterns, and make data-driven predictions across diverse scientific fields. Automate the analysis of large or complex data sets using AI algorithms and leverage machine learning models to improve diagnostics, accelerate drug discovery, and refine experimental design. Discover the best AI/ML software, platforms, and analytical tools in our peer-reviewed product directory: compare features, read customer reviews, and request pricing directly from manufacturers.Animal ModelsThe use of non-human animals in experiments or behavorial observations. The research is conducted inside universities, medical schools, pharmaceutical companies, farms, defence establishments, and commercial facilities that provide animal-testing services to industry. It includes pure research such as genetics, developmental biology, behavioral studies, as well as applied research such as pharmaceutical testing in pre-clinical, before human, studies. Inflammatory Diseases
Unveiling the drivers of inflammatory bowel disease (IBD)