ResourceForensics

Analysis of parabens using UHPLC

14 Mar 2022

Parabens, esters of p-hydroxybenzoic acid, are used as preservatives in cosmetics and foods. In this application note, JASCO demonstrates how UHPLC can be applied to provide a high throughput method to determine the content of esters.

LC-4000 Series HPLC pumps

JASCO (USA)

The LC-4000 series HPLC pumps include expansion bays that allow a simple pump module to be transformed into a powerful solvent delivery system.Accessory modules can be installed in the LC-4000 series pump for use with virtually any solvent delivery requirement. Features Upgrade and Expansion Eliminating pulsation Pump configurations Solvent Mixing Solvent Degassing Preparative and Semi-preparative pumps

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LC-4000 Series Integrated HPLC and UHPLC Systems

JASCO (USA)

The LC-4000 Series is the latest in a long history of innovative HPLC systems developed by JASCO reaching all the way back to the start of commercial HPLC in the early 1970s. The concept of the integrated LC-4000 series HPLC provides key separation platforms at 50MPa, 70MPa and 130MPa which correspond to conventional HPLC, the increasingly popular Rapid Analysis (RHPLC) and sub 2um UHPLC, respectively. Each platform is supplied with a dedicated pump and autosampler matched to the operating pressure and all three platforms share common detectors optimized for high-speed 100Hz acquisition and the narrow peak shapes common to both RHPLC and UHPLC. Features 300mm wide footprint Each system component is completely stackable into a modest height The system is fully integrated with complete system monitoring All user replaceable components are accessible through the front panel Vertical leak/drain system to channel away solvent Integrated earthquake securing option All detectors include 100Hz acquistion with interchangeable flowcells Preparative HPLC Systems The LC-4000 preparative HPLC systems includes three platform options Up to 20mL/min for columns up to 21.2mm ID Up to 50mL/min for columns up to 3cm ID Up to 120mL/min for columns up to 5cm ID

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Food and Beverage AnalyzersFood and Beverage Analyzers are commonly used to provide information about the chemical composition, structure and physical properties of food materials.Particle CharacterizationParticle characterization instruments are used to determine particle size distribution, shape, surface area, zeta potential, density and porosity of particles and materials. Multiple tecchniques are available for determining particle size, shape and count including dynamic light scattering (DLS), laser diffraction, electrozone (Coulter technique), imaging particle analysis and single particle optical sensing. Determine the density of your material with a gas pycnometer or examine its surface area and porosity with gas adsorption analyzers and mercury porosimeters. Find the best particle characterization instruments in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Quality ControlQuality control is needed in all production processes. Quality control is a monitoring procedure or set of procedures that are put in place to ensure that a manufactured product adheres to a defined set of quality criteria. High ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.Quality TestingQuality testing ensures that products meet required specifications and safety standards in various industries, including pharmaceuticals, food, and materials. It is essential for maintaining product quality and consumer safety. Explore quality testing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Food TestingFood testing refers to a variety experiments including PCR, mass spectrometry, processing, QuEChERS, analyzing and Kjeldahl.Elemental AnalysisElemental analysis involves determining the elemental composition of a sample, often used in environmental, pharmaceutical, and material sciences. Techniques like ICP-MS, X-ray fluorescence, and atomic absorption spectroscopy allow precise quantification of elements such as metals and nonmetals in complex matrices. Browse our peer-reviewed product directory to find the best elemental analysis tools, compare products, check reviews, and get pricing directly from manufacturers.CosmeticsOrganic Acids