Scale-up Products & Reviews

The NucleoCounter® NC-202™ automated cell counter is our 3rd generation cassette-based image cytometer. Featuring improved hardware and new NC-View™ software, we take precision, speed and data management to new levels.

NucleoCounter® instruments provide platforms for determination of viability and cell count as well as advanced image analysis of yeast, veterinary semen, insect cells and mammalian cells, both primary cells and cell cultures, including cells in aggregate or microcarrier cultures.

The NucleoCounter® NC-3000™ is an advanced image cytometer utilizing fluorescence imaging to characterize cell properties. The NC-3000™ can perform high-speed cell count and viability analyses and it includes plug-and-play analytical assays of mammalian, yeast and insect cells. Pre-defined assays include a unique 5-minute cell cycle assay, a selection of apoptosis assays and a GFP transfection efficiency assay.

DASGIP Parallel Bioreactor Systems for R&D and process development in both cell culture and microbiology allow for advanced bioprocess control and automation. Parallel processing, precise control of all relevant parameters, user-defined profiles and innumerable automation features result in accelerated and highly efficient process development. Our DASware software solutions support DoE, process historians and comprehensive…

Recombinant, expressed in Pichia pastoris, ATPase ≥1000 units/mg protein, lyophilized powder.

CytoPak™ GMP Human IL-2 Protein comes in sterile, closed-system packaging for seamless integration into ex vivo clinical production. The medical-grade multilayer bag features weldable tubing options, allowing direct connection to GMP media bags. Its liquid form eliminates the need for reconstitution, enhancing safety and ease of use.

3M™ Harvest RC Centrate Chromatographic Clarifier is a single stage single-use chromatographic clarification solution designed to effectively clarify modern cell culture centrates. Centrate clarification using 3M™ Harvest RC Centrate Chromatographic Clarifier may provide many benefits including process compression, high product recovery, and improved process economics.

ActiveMax® Streptavidin μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm with streptavidin on its surface. Streptavidin is a tetrameric protein providing 4 high-affinity biotin binding sites, which make it possible to fast prepare and customize your own sterile protein/antibody coupled beads for cell based assay, cell sorting, cell therapy process development and manufacturing use.

CytoPak™ GMP Human IL-7 Protein comes in sterile, closed-system packaging for seamless integration into ex vivo clinical production. The medical-grade multilayer bag features weldable tubing options, enabling direct connection to GMP media bags. Its liquid form eliminates the need for reconstitution, enhancing safety and ease of use.

Interferon-gamma (IFN-gamma ), also known as type II or immune interferon, exerts a wide range of immunoregulatory activities and is considered to be the prototype proinflammatory cytokine. IFN-gamma is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells.

GMP ActiveMax® Human T Cell Activation/Expansion CD3/CD28 Beads are 5.5 μm magnetic beads coated with GMP-grade CD3/CD28 antibodies, mimicking APC stimulation. Manufactured in a GMP-compliant, animal-free process, they enable in vitro isolation, stimulation, and expansion of T cells (CD3+, CD4+, CD8+, PBMC) for clinical and preclinical research.

ACRO offers two GMP-grade DLL4 proteins, GMP-DL4H27 (Flagship Product) and GMP-DL4H28 (Complementary Product), designed for iPSC cell culture and differentiation applications. While both proteins undergo similar manufacturing processes with minor procedural variations, they are strategically positioned to address distinct user needs.

The 3M™ Harvest RC Chromatographic Clarifier is a single stage single-use chromatographic clarification solution designed as an efficient option for harvesting and clarification of modern cell cultures. Clarification using 3M™ Harvest RC Chromatographic Clarifier may provide many benefits including fewer processing steps, higher yield and lower production time and costs.

Recombinant IL-2 is widely used in cell culture for the expansion of T cells. In cell culture, IL-2 is a frequently used cytokine for the proliferation, differentiation, and increased antibody secretion of B cells as they transform into plasma cells in vitro.

GMP Human Laminin 521 Protein supports feeder-free PSC culture, maintaining growth and stemness without differentiation for over 10 passages. It’s produced in a GMP-compliant, animal-free process with strict QC testing to ensure quality. Designed for clinical research, it enables a seamless transition from preclinical studies to cell therapy applications.

Interleukin 15 (IL-15) is a widely expressed 14 kDa cytokine that is structurally and functionally related to IL-2 and plays an important role in many immunological diseasesreticulum. The dominant mechanism of IL-15 action is known as transpresentation.GMP IL-7 and GMP IL-15 are commonly used in combination for ex vivo expansion of T cells for cellular therapies.

Interleukin-4 (IL-4), also known as B cell-stimulatory factor-1, is a monomeric, approximately 13 kDa‑18 kDa Th2 cytokine that shows pleiotropic effects during immune responses.Due to its role in the differentiation of certain immune cell types, IL-4 is commonly used in combination with other growth factors to transform induced pluripotent stem cells into dendritic cells in high numbers.

ProVance™ columns are a high-performance disposable chromatography solution to help meet the growing demand for downstream purification. Until now, there has not been a cost-effective Protein A chromatography option for single-use manufacturing facilities. ProVance™ columns combine Grace proprietary incompressible silica with cost-effective Protein A and disposable column hardware.Grace is the world's largest supplier of spec…

A micro-well, plate-based multi-channel bright field and 4 fluorescent channels imaging cytometer for 2D and 3D culture using both adherent and suspension cells.

A micro-well, plate-based bright field imaging cytometer for 2D and 3D culture using both adherent and suspension cells.

A micro-well, plate-based multi-channel bright field and 3 fluorescent channels imaging cytometer for 2D and 3D culture using both adherent and suspension cells.

Chemical process safety by design.

Improve reaction understanding with real-time in situ analysis.

Unattended, representative sampling for a wide range of chemical reactions.