NSE-p25 mice were created by pronuclear injection of an NSE-p25 transgene, produced internally at Pfizer, with transplantation of embryos to pseudopregnant CD-1 females. At weaning genomic DNA was isolated from tail tissue and founder transgenics were identified by PCR that specifically amplified DNA sequences from the human p25 cDNA. Founder mice were bred to FVB/N mates and transgenic offspring were used to maintain the tra…
Developed by C.C. Little in 1921, from a mating of Miss Abby Lathrop’s stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To Hall in 1948 from The Jackson Laboratory. To NIH in 1951 from The Jackson Laboratory at F32. To Charles River in 1974 from NIH. Model Properties: Coat Color: Black MHC Haplotype: H2b Ideal For: general multipurpose model, diet-induced obesity, transgenic…
Silvers and Billingham began brother x sister matings with selection for histocompatibility in 1958 from a brown mutation in a stock of wild rats maintained by King and Aptekman in a pen-bred colony of rats trapped from the wild in 1930 by King at the Wistar Institute. To Charles River from Radiobiology Institute, Netherlands in 1976. Model Properties: Coat Color: Non-agouti brown MHC Haplotype: RT1n Ideal For: Geneti…
This immunodeficient nude mouse originated from NIH and was originally thought to be a BALB/c congenic. It was later determined that it was not inbred and is therefore maintained as an outbred. It is not associated with any stock or strain. The animal lacks a thymus, is unable to produce T cells, and is therefore immunodeficient. To Charles River from NCI in 2010. Model Properties: Coat Color: Hairless, albino background…
The New Zealand White rabbit was obtained in 1991 by Charles River Canada (CRC) from Kitayama Labs K.K. of Nagano Prefecture, Japan. Model Properties: Coat Color: White (albino) Ideal For: General multipurpose model Strain Code: 052
Optim is an innovative analytical instrument designed to probe multiple protein stability-indicating parameters at high speed using ultra-low sample volumes of proteins and other molecules. Compact and robust, using a light scattering and fluorescence technology in a configuration never seen before and controlled by an all-new easy-to-use intuitive software package, the Optim 2 has been designed to reduce the time and cost of…
Formulation Development SpecialistsWith a keen understanding of early stage development and clinical trial requirements, Aesica guides their customers through the processes of new medicine and material development for Phase 1 and Phase 2 clinical trials. They understand that their customers also need to maximise their budget effectiveness by minimising the amount of experimentation without sacrificing quality levels.Typical do…
In the fast growing Biopharma market, the need for ultra clean sterile packaging is growing at a high speed, often driven by regulatory authorities and cGMP regulations. Eliminating every risk of delivering a contaminated parenteral drug that might be hazardous to a patient's health or even his life is the key concern that drives these regulations.The source for all your Cleanroom Packaging - with the Newform™ product line, r…
HT3000A is a liquid GC autosampler that offers reliability and superior performance for all GC-GCMS applications. The HT3000A is the most compact autosampler on the market, with a near-to-zero requirement for bench space, while offering a top-class sample capacity (121 positions for 2ml vials). The sample rack can be removed for sample loading or preparation, or for storage elsewhere.It can be easily installed on all the GC a…
The HT2000H Headspace autosampler is made to meet the needs of static headspace injection for GC analysis. HTA's proven superior headspace technology is based on a high performing gastight syringe. Through a short flow path, it eliminates any source of error, such as vial pressurization, valve switching, loop filling or transfer lines assuring repeatability (RSD up to To obtain the highest sample throughput, the progressive s…
HT4000L is an HPLC autosampler for high presise injection into HPLC, UHPLC, LC/MS and IC systems. HT4000L is lab automation ready. In fact HT4000L besides working as a standard HPLC autosampler, can take care of many sample preparation tasks as no standard autosampler has been able to assist up to now. Basic sample preparation capabilities includes dilution, precolumn derivatization, pH spiking and internal standard addition…
HT4000A is a sample preparation workstation that allows automation of sample preparation procedures by taking care of a large number of operations such as liquid handling, purification or filtration (including Solid Phase Extraction (SPE), Micro Extraction by Packed Sorbent (MEPS), Whatman® Mini-UniPrep® syringeless vials, syringe-filters and liquid/liquid extraction (LLE)), tracking and further sample processing such as vorte…
HT3100A is a liquid GC autosampler that offers automation for processing up to 15 unattended samples. It handles the most sophisticated sampling techniques: Multi-phase sampling, Sandwich injection, Priority sampling, Ambient headspace sampling, Nanoliter injection. It can be easily installed on all the GC and GC/MS systems available in the market, because of flexibility and modular configuration. It can be configured to serv…
HT3200A is a liquid GC autosampler, that takes advantage of today’s latest technology to deliver even greater reliability, performance, as well as offering an extraordinary GLP experience. The HT3200A has a top class sample capacity: no other offers so many samples (209 2mL sample vials) with near-to-zero bench space requirements.Key features: Easy to use Support all GCs of your lab Fast injection technology Versatili…
The HT2100H is an inexpensive, simple-to-use, as well as reliable headspace unit. With all the quality and reliability you expect, the HT2100H headspace sampler offers exactly the features you need — at a price to fit your budget.The HT2100H is a quality, cost-effective alternative to manual headspace. While manual sampling techniques are simple and inexpensive, they are also tedious, subject to human error and they are not a…
HT310L is a cost-effective HPLC autosampler, that offers automation for processing up to 10 unattended samples. By its competitive pricing is the alternative to the manual injector for users that cares about reproducibility and accuracy. HT310L fits every HPLC system, and its direct syringe injection minimizes dead volume, reduces carry-over and improves repeatability. Full and partial loop are both performed with very accura…
Most demanding applications and finest integrated vacuum control capabilities. Includes leading safety standards and features for superior ease of use and reduced cost of ownership. Reduce your process times significantly by using three programs for automated distillation.Hei-VAP Precision Features: Available in hand lift or motor lift configurations Experience the advantages of our large 4.3 '' color graphic display wh…
Marken’s network fulfills the global movement of API from the point of manufacturing to CMOs and primary packagers. Marken optimizes API logistics around the globe with continuous temperature monitoring, documented transit custody and a worldwide network of offices, providing end-to-end quality-assured supply chain services.With Marken’s experience and expertise they excel in assisting companies to achieve the most expeditiou…
Marken offers validated packaging solutions for the widest range of temperatures to ensure that your products maintain their integrity throughout the shipment. BIOsystem boxes are designed and engineered specifically for the transportation of frozen and controlled ambient biologics. Your samples have specific temperature profiles that must be strictly maintained to preserve their efficacy. Marken is uniquely qualified to prov…
This complete service package is a cost-effective way to genotype large sample and SNP numbers for plant, livestock, and aquaculture species.
The first step in any study investigating genetic differences in an organism of interest is the purification of DNA, and the nucleic acid extraction teams at LGC provide DNA extraction services to meet the demands of any project. Depending on project size, specific customer requirements and the biological background of the project, we can provide an optimised solution using any one, or a combination, of our propietary extrac…
The Meridian 3 ™ system provides non-contact, continuous reagent dispensing, ideal for genotyping, standard PCR and other applications. Originally developed for our own genotyping services laboratory, laboratories worldwide now use the Meridian technology to meet their high-throughput and efficiency needs.
The Aurora 1030C TOC Analyzer processes aqueous samples for analysis of the total organic carbon (TOC), total inorganic carbon (TIC), and non-purgeable organic carbon (NPOC) content of the samples. Samples containing 100 ppb to 30,000 ppm of organic carbon can be analyzed. The Aurora 1030C supports USEPA-approved methods, Standard Methods, ASTM, DIN/ISO/CEN, and EU Methods. Depending upon the protocol employed, up to 300 samp…
CAP-412 Vertical Laminar Flow Open Base Clean Benches create a freestanding ultra-clean mini-environment. CAP412 Mode OB Features: Open Base allows the unit to be placed over existing work tables or equipment Welded 16 gauge steel filter cabinet with a white powder coat finish Welded 11 gauge 2x4 tubular steel lower frame with a white powder coat finish White vinyl coated steel back panel 80 Mil clear flexible vin…
Reliable detection of copy number changes for research into a range of genetic disorders. CytoSure Molecular Arrays are designed to accurately identify small intragenic copy number variations (CNVs) in genes associated with a variety of disorders. The content for each array has been designed and optimised in collaboration with leading molecular genetics experts at Emory University. In addition to pre-designed catalogue arrays…
