Athymic Nude Mouse Model

This immunodeficient nude mouse originated from NIH and was originally thought to be a BALB/c congenic. It was later determined that it was not inbred and is therefore maintained as an outbred. It is not associated with any stock or strain. The animal lacks a thymus, is unable to produce T cells, and is therefore immunodeficient. To Charles River from NCI in 2010. Model Properties: Coat Color: Hairless, albino background…

Charles River

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Description

This immunodeficient nude mouse originated from NIH and was originally thought to be a BALB/c congenic. It was later determined that it was not inbred and is therefore maintained as an outbred. It is not associated with any stock or strain. The animal lacks a thymus, is unable to produce T cells, and is therefore immunodeficient. To Charles River from NCI in 2010.

Model Properties:

  • Coat Color: Hairless, albino background
  • Ideal For: Tumor biology and xenograft research
  • Strain Code: 491 (Heterozygous, not immunodeficient), 490 (Homozygous)

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