Drug discovery > Pre-Clinical Development Products & Reviews

The Gyrolab® Mouse IFN-gamma Kit enables rapid quantification of murine IFN-gamma in serum samples

OpenSPR® provides real-time, label-free SPR data at a fraction of the cost of existing solutions. Highly sensitive while being simple to maintain and operate, OpenSPR has been used by hundreds of researchers to generate publication-quality data.

BioIVT’s extensive, highly characterized, normal and disease-state tissue samples are collected and prepared under strict ethical and QC policies and feature detailed clinical data as well as pathologist verification of disease tissue blocks to help ensure the accuracy of your research. Custom collections or extensive inventory are available from a diverse donor pool or any commercially available species.

Accelerate oncology drug development with Crown Bioscience’s PDX Mouse Clinical Trials. Leverage the world’s largest clinically relevant PDX collection to model patient tumor heterogeneity, predict clinical outcomes, discover biomarkers, and optimize drug strategies. Improve clinical translation and reduce attrition with highly predictive, patient-relevant insights.

CrownSyn™: Quantify and visualize drug synergy, antagonism, or additivity in vitro and in vivo with Crown Bioscience’s robust bioinformatics platform—empowering oncology researchers to optimize combination therapies with confidence.

Delve into biomarker discovery and drug development with Crown Bioscience’s next-generation proteomics services—leveraging 4D-DIA technology for deep, reproducible protein profiling and post-translational modification analysis.

Unlock immune insights with Crown Bioscience’s high-throughput flow cytometry—precisely characterize immune cell populations across tissues to elucidate drug mechanisms, assess pharmacodynamics, and optimize immunotherapies.

BioIVT is the leading provider of quality, highly characterized, ethically procured ADME research products, featuring custom preparation or extensive ready-to-ship inventory, large lot sizes and expert support.

The Rexxip™ Scouting Pack enables screening of buffers for assay optimisation

Isolated immune cells play a crucial role across the stages of drug discovery and development from biomarker and target identification through screening and safety assessment to manufacturing. They can be used to create disease models, cell lines, gene editing techniques and more.

Myelotracker® is a cutting-edge fluorescent probe that enables precise detection of neutrophils—essential immune cells—in both blood and tissue samples. It offers researchers a dependable tool for exploring inflammation, infections, and immune system activity.

BioIVT has the expertise in the processes required for ethical acquisition of biospecimens that cover a wide range of disease states and the protocols needed to produce reliable data. With over 425 IRB-approved clinical sites, BioIVT provides clinical specimens for nearly all disease states.

Sf9 HCP 3G Solution for Gyrolab for the detection of Sf9 host cell protein impurities in bioprocess samples.

E.Coli HCP 2G Solution for Gyrolab enables detection of E. coli HCP impurities in products manufactured by recombinant expression.

BioIVT supplies high quality, ready to ship or custom plasma, serum, and whole blood—both normal and disease-state—collected from a diverse pool of consented donors under IRB-approved protocols or a wide variety of species.

Accelerate the development of your immuno-oncology drugs with Crown Bioscience’s large panel of immunocompetent syngeneic models.

The Gyrolab® Mouse IL-6 Kit enables rapid quantification of murine IL-6 in serum samples

Monoclonal and polyclonal antibodies with validated performance for the precise detection of disease biomarkers in a wide range of clinical and research immunoassays.

Crown Bioscience’s preclinical biomarker services help identify, validate, and analyze biomarkers across diverse in vitro and in vivo cancer models. Using multi-omics platforms and expert bioinformatics, these services support drug mechanism studies, patient stratification, and companion diagnostic development to guide oncology drug discovery.

The open organ-on-chip platform

As the world's largest private repository of human cerebrospinal fluid, BioIVT’s Center for NeuroExcellence offers 35,000+ healthy and 113,000+ diseased donor samples allowing for comparative studies and precise control matching. The samples are ethically collected following strict quality standards and feature detailed clinical data and matching blood, plasma, or sera.

The Gyrolab® Mouse IL-10 Kit enables rapid quantification of murine IL-10 in serum samples

Recombinant proteins specifically relevant as E3 ligases or target proteins for Proteolysis Targeting Chimeras (PROTACs), enabling the development of this novel targeted protein degradation technology.

Gyrolab® Bioaffy™ 4000, the newest member of the Gyrolab Bioaffy family, offers 2-6 fold extended sensitivity for PK and biomarker analysis compared to Gyrolab Bioaffy 1000.

KREX™ i-Ome™ Discovery Services enable highly multiplexed autoantibody profiling for rapid, reproducible discovery across diverse diseases. The platform measures antibody binding to 1,800+ full-length, correctly folded human proteins – preserving conformational epitopes for highly specific and biologically relevant autoantibody detection. It provides valuable insight into immune responses in health, disease and treatment.