Drug Discovery & Development Products & Reviews

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Mouse microRNA Microarrays generate complete microRNA profiles for broad insight into mouse expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase 16.0  Mouse and mouse viral miRNAs represented  Optimal sensitivity and specificity through unique pro…

Agilent Rat microRNA Microarrays generate complete microRNA expression profiles to allow broad insight into rat expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase  Optimal sensitivity and specificity through unique probe design method  8 x 15 K slide fo…

Agilent Rat microRNA Microarrays generate complete microRNA expression profiles to allow broad insight into rat expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase  Optimal sensitivity and specificity through unique probe design method  8 x 15 K slide fo…

Agilent Rat microRNA Microarrays generate complete microRNA expression profiles to allow broad insight into rat expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase  Optimal sensitivity and specificity through unique probe design method  8 x 15 K slide fo…

Agilent Rat microRNA Microarrays generate complete microRNA expression profiles to allow broad insight into rat expression and regulation. Probe design, coupled with a unique labeling method, works in concert to provide the optimal sensitivity and specificity that your work demands.  Content regularly updated from the Sanger miRBase  Optimal sensitivity and specificity through unique probe design method  8 x 15 K slide fo…

KREX™ i-Ome™ Discovery Services enable highly multiplexed autoantibody profiling for rapid, reproducible discovery across diverse diseases. The platform measures antibody binding to 1,800+ full-length, correctly folded human proteins – preserving conformational epitopes for highly specific and biologically relevant autoantibody detection. It provides valuable insight into immune responses in health, disease and treatment.

Streamline Mass Spec Sample Preparation. MassXtract STAR Line combines all the tools you need to fully automate solid-phase extraction and protein precipitation workflows.

CyBio FeliX SELECT Head - We Normalize Speed The SELECT Head revolutionises liquid handling with 8 independent channels and volumes. Simplify complex transfers by executing directly from your CSV files, liberating you from complicated programming. Avoid slow pipetting bottlenecks in your workflows and automate faster than with a single tip.

The Queen of high-throughput protein stability characterization. Aunty is the fastest and highest throughput protein stability characterization tool on the planet.

Designed for accuracy and speed, Omnia Discovery optimizes workflows, reduces reagent waste, and offers value for advancing microfluidic and assay development.‍

Stop gambling on cycle numbers. The icon96 uses iconPCR™ technology with AutoNorm™ software to provide real-time fluorescence feedback in each of 96 independent wells, preventing under-amplification dropouts and over-amplification artifacts—delivering balanced, sequencing-ready libraries without manual quantification or normalization.

The new standard in benchtop sequencing speed and simplicity

High-throughput boosting. Compatible with manual workflows and liquid handlers.

Real-Time Live Cell Imaging and Analysis System

Our Metabolite Identification service for peptides utilizes HRMS to characterize peptide metabolism (e.g., hydrolysis, oxidation, glucuronidation). The assay identifies and semi-quantifies metabolites in plasma/tissues, enabling ADME profiling (clearance, bioavailability), toxicity screening (reactive metabolites) and peptide optimization (PK/PD enhancement). Integrated with preclinical data, it supports metabolically stable p…

Our Comprehensive In Vitro Proarrhythmia Assay (CiPA) service assesses proarrhythmic potential of compounds beyond hERG inhibition, integrating effects on multiple cardiac ion channels and human iPSC-derived cardiomyocytes via patch clamp and multi-well MEA platforms. Aligned with FDA's CiPA initiative and ICH E14/S7B guidelines, it predicts QT prolongation and TdP risks for enhanced specificity in early drug safety evaluation…

Our Protein Binding Platform assesses drug-protein interactions using equilibrium dialysis and ultracentrifugation methods to determine unbound fractions and distribution in biological samples including plasma, blood, tissues, and cells. This essential ADME service evaluates reversible drug transfer between compartments, providing insights into pharmacokinetics, bioavailability, and potential interactions.

Our hERG Safety Screening service employs the Synchropatch-384 automated patch clamp system to assess compound effects on the hERG potassium channel. This high-throughput assay detects inhibitors that may prolong QT intervals and cause arrhythmias, aiding early drug safety evaluation. With precise data under physiological conditions, it supports regulatory compliance to advance safer therapeutics. 

Our Metabolite Identification service employs HRMS /LC-MS/MS to decode degradation pathways of antisense oligonucleotides (ASOs), siRNAs, and modified variants, identifying chain-shortened metabolites (5’/3’ cleavage), phosphorothioate changes (desulfurization, inversion) and base/nucleotide alterations (deamination/depurination). Through plasma/tissue/cell analysis, we reveal metabolic stability, biodistribution, and exonucle…

Our Metabolite Identification service for Antibody-Drug Conjugates (ADCs) applies immuno-capture and HRMS to detect payload-containing catabolites, linker cleavages, and biotransformations in biological samples. This targeted assay quantifies free payloads, metabolites, and intact conjugates, assessing stability and off-target risks. Essential for ADC development, it informs payload design and pharmacokinetics, ensuring compli…

Our Cassette and Discrete PK Study service evaluates pharmacokinetic profiles of small molecules in key preclinical species: rat, mouse, dog, and monkey. It uses cassette dosing for high-throughput screening of multiple compounds simultaneously and discrete dosing for precise individual assessments for ADME parameters. This aids in early drug optimization, predicting human PK, and ensuring regulatory compliance for safer candi…

wavePREP is an efficient, rapid, and safe tool for the post-processing step in the oligos production. Its process combines cleavage and deprotection into a single step, ensuring both a superior workflow and product yields by removing the evaporation phase.

The Milestone synthWAVE is designed for safe, reliable and reproducible scale-up of microwave enhanced chemical reactions. The synthWAVE is capable of higher temperature and pressure than any other microwave reactors. Milestone synthWAVE features the unmatched Single Reaction Chamber (SRC) patented technology that ensures scale, reaction screening, highest temperature and pressure. It is able to handle single or multiple react…