Fully automated PCR systems for scalable RUO SARS-CoV-2 detection
Keep up with fluctuating testing demands in an economically viable way due to minimized labor costs enabled by automated sample processing, amplification, and data analysis workflows.
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The scientific community continues to call for large-scale and frequent testing as a key response to help manage the spread of COVID-19. Incorporating this strategy into COVID-19 testing will support economic recovery and a return to pre-pandemic life. Current PCR-based testing efforts are crippled by constraints of an unstable supply chain of instruments, consumables and reagents, and by PCR testing systems that can process only a few thousand tests per day. LGC Biosearch Technologies’ IntelliQube™-based SARS-CoV-2 testing workflow is redefining high-throughput to 35,000 patient tests per day on a single system. The Nexar™-based testing workflow is an ultra-high-throughput automated platform that can complete 110,000+ test results per 24 hours. The FDA granted emergency use authorization (EUA) for this system for testing during the Public Health Emergency.
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IntelliQube™ integrated PCR workflow
LGC Diagnostics and Genomics - Rapid Genomics Genotyping SolutionsFully Automated PCR Setup, Amplification and Analysis System. The IntelliQube is the first fully automated and high-throughput instrument featuring seamless integration of liquid handling, thermal cycling, detection, and data analysis. The IntelliQube supports quantitative real-time PCR, end-point PCR, and isothermal chemistries, allowing you to realize the benefits of inline automation enabled by the innovative Array Tape™ consumable. IntelliQube leverages best-in-class multi-functional dispensing for high speed liquid handling in 384- or 768-well Array Tape™. Precise sample dispensing into Array Tape is handled by an interchangeable CyBi® FeliX 96- or 384-channel pipetting head. The IntelliQube supports inline amplification with a Peltier thermal cycling block designed specifically for Array Tape™. Due to a unique block design and surface geometry, both 384- and 768-well Array Tape are supported, without requiring a block change. The IntelliQube features an advanced optical system optimized for inline fluorescence detection in Array Tape. Filtered LEDs are optimized for a variety of commonly used fluorophores excited within the range of 480-620 nm. A high-resolution CCD camera supports detection of fluorescence intensity within 5 detection channels for dyes emitting within the range of 510-705 nm. Multiplex data capture for all 5 optical channels can occur in as little as 10 seconds. Benefits: Walk-away operation Increased efficiency of lab personnel Reduced chemistry costs Increased throughput Reduced consumable costs
Hydrocycler2™
LGC Diagnostics and Genomics - Rapid Genomics Genotyping SolutionsCombining throughput, efficiency and robust design, the Hydrocycler range of water bath thermal cyclers offer an attractive alternative to traditional Peltier-based thermal cyclers for high-throughput PCR.
Array Tape™
LGC Diagnostics and Genomics - Rapid Genomics Genotyping SolutionsArray Tape is a thin (0.3 mm) and flexible continuous polymer strip, serially embossed with reaction wells in customised volumes and formats including 96- and 384-well array. A reel with 40 meters of Array Tape carries 277 equivalents of a 384-well plate (106, 368 reaction wells). Array Tape is the ideal consumable for fast, streamlined and continuous lab workflow processes.
Nexar™
LGC Diagnostics and Genomics - Rapid Genomics Genotyping SolutionsNexar™ is a modular inline liquid handling and assay processing system offering a highly scalable solution for PCR-based genotyping.
Soellex™ - Waterbath thermocycling
LGC Diagnostics and Genomics - Rapid Genomics Genotyping SolutionsThe Soellex™ is an ultra-high-throughput end-point PCR thermal cycler leveraging a 3-chamber water bath.
Araya™ - Assay detection
LGC Diagnostics and Genomics - Rapid Genomics Genotyping SolutionsRapid fluorescence detection for PCR and isothermal amplification. The Araya is a top-read fluorescence detector.
