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Your end of year playlist: 10 top videos on The Scientists’ Channel in 2019

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We look back at a selection of this year’s best interviews with some of the world's leading experts

19 Dec 2019
Laura Sisman
Administrator / Office Personnel

Editorial article

The Scientists’ Channel is an independent video platform for scientists, clinicians, and laboratory experts around the world to share the latest innovations in their fields. From clinical diagnostics to NMR to cell culture, hear from leading researchers about which technologies and techniques they use to advance their work. To keep up with the excitement of multiple scientific communities, The Scientists’ Channel takes you behind the scenes of the major annual conferences, from SLAS to Pittcon, and this summer launched a new Cannabis Testing channel to keep you at the cutting edge of this growing industry. As we approach the end of the year, here we bring you our top ten The Scientists’ Channel interviews from 2019:

Links between the human microbiome and cardiovascular health

Sofia Forslund
Dr. Sofia Forslund, junior group leader at ECRC (MDC/Charité, Berlin), explains how she hopes that the modeling of missing microbial data will lead to more personalized therapeutics for conditions such as hypertension. Forslund also highlights the importance of avoiding contamination during vital research procedures and explains the necessity of equipment such as NuAire's biosafety cabinets. The rising prevalence of non-alcoholic fatty liver disease Prof. Zobair M. Younossi, Professor and Chairman of the Department of Medicine at Inova Fairfax Hospital in Falls Church, Virginia, talks about the epidemiology of non-alcoholic fatty liver disease (NAFLD), addressing why there is a global need for more awareness and why the current approach to clinical care needs to change. Untangling the structure of disordered proteins in Alzheimer's disease with ultra-high field NMR Professor Christian Griesinger, Head of NMR-Based Structural Biology at the Max Planck Institute for Biophysical Chemistry, is using ultra-high field NMR to investigate intrinsically disordered proteins (IDPs). The structure of IDPs is important in diseases such as neurodegenerative diseases and Griesinger's research allows the function, or malfunction, of such IDPs to be investigated. Analysis of pesticides in cannabis products Dr. Nathaly Reyes Garcés and Colton Myers explain how Restek is overcoming challenges in the cannabis testing industry by helping to create bespoke workflows and method development in the face of ongoing changes within the industry, new regulations coming into place, and state-to-state differences in the United States. Quality control assessments for cannabis Dr. Jonathan Speare, from White Buffalo Laboratories, discusses quality assurance requirements and outlines how quantifying marijuana testing is changing the cannabis industry. Speare explains how Waters helps White Buffalo Laboratories test for different cannabinoids and other chemicals such as pesticides and mycotoxins and how these tests can be used to provide a safe product. Discover more about the emerging field of cannabis on The Scientists' Channel>> An interview with Nobel laureate Sir Fraser Stoddart We hear from Nobel laureate Sir Fraser Stoddart about the most recent discoveries, studies, and technologies in chemistry. Stoddart, along with Jean-Pierre Sauvage and Ben Feringa, won the 2016 Nobel Prize in Chemistry for the design and synthesis of artificial molecular machines. A novel two-step pathway to detect liver cirrhosis earlier Dr. Ankur Srivastava, Consultant Gastroenterologist and Hepatologist at Southmead Hospital, North Bristol Trust, U.K., discusses his two-step primary care pathway approach of utilizing non-invasive tests to reduce unnecessary referrals and improve detection of severe disease in patients with non-alcoholic fatty liver disease (NAFLD).  NMR saved despite university damage during Hurricane Maria Find out how one dedicated scientist at the University of Puerto Rico kept his lab’s prized Bruker NMR running in the wake of one of the most destructive hurricane seasons on record. Dr. Melvin De Jesus Flores describes how his efforts following Hurricane Maria in 2017 led to him successfully saving his NMR and won him a Scientists' Choice Award, along with Bruker. Studying the structural biology and biophysics of HIV with NMR Dr. Tatyana Polenova from the University of Delaware is using solid-state NMR spectroscopy to look at the molecular structure of viruses with atomic resolution. Polenova explains how her work is providing fundamental insight into the structure of HIV, pushing forward understanding of the virus, and helping to advance the development of a cure for the disease. A novel target to inhibit glioblastoma invasion Dr. Aleksandra Dukic, a postdoctoral researcher at the Institute for Cancer Research, Oslo University Hospital, describes a novel target for inhibiting glioblastoma cancer invasion into surrounding brain tissue and the importance of this work in addressing the need for innovative therapeutics to combat this aggressive cancer. Watch more videos on The Scientists' Channel>>

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NMR and EPR SpectroscopyNuclear magnetic resonance (NMR) spectroscopy is used to resolve the local chemical environment of atomic nuclei with spin, revealing information on molecular structure, dynamic processes and chemical reactions of organic molecules, from proteins to synthetics. Electron paramagnetic resonance (EPR) also known as electron spin resonance (ESR) spectroscopy is used to detect and quantify paramagnetic species in a sample, including free radicals as transition metal ions. By immersing the sample in a strong magnetic field, both NMR and EPR spectrometers probe the sample with either radio waves or microwaves respectively. A range of benchtop, solid-state and time domain NMR spectrometers & EPR spectrometers are available, as well as NMR tubes, NMR solvents, software, coils, and magnets. Find the best NMR & EPR equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.RegulatoryPharmaceutical regulations impact on all areas of drug development, manufacture and control and supply. Services are provided from the early stages of drug development and clinical trials through to dossier submission, approval and marketing. Regulatory also includes submission of analytical studies from the pharmaceutical product and safety. Contamination PreventionContamination prevention aims to control and minimize the risk of contamination during experiments. Biological safety cabinets and sterilization equipment are examples of technologies used to prevent contamination.HIV and AIDSBlood tests are the most common way to identify and monitor HIV and AIDS. Current methods include ELISA, Western blot, RT-PCR viral load and CD4/8 testing. Areas for development include point-of-care assays for use in developing countries, and self-testing ‘at home’ HIV kits.Liver DiseaseCancer ResearchCancer research aims to understand the mechanisms of cancer development and progression to improve prevention, diagnosis, and treatment. From molecular biology to clinical trials, research spans a wide range of disciplines, including immunotherapy, targeted therapies, and drug discovery. Explore the best cancer research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.MicrobiomeMicrobiome research focuses on the complex communities of microorganisms living in and on humans, animals, plants, and environments. It plays a crucial role in health, disease, and ecological balance. Explore tools and resources for microbiome analysis, including sequencing platforms and bioinformatics software.NMRVirusesViruses are microscopic pathogens that require a host cell to replicate. Understanding their structure, replication cycle, and impact on the immune system is crucial in developing effective treatments, vaccines, and diagnostic methods. Research continues to focus on emerging viral diseases and antiviral drug discovery. Explore solutions for virus research, detection, and treatment in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.Cardiovascular DiseaseCardiovascular disease refers to a group of disorders of the heart and blood vessels, including heart attacks, strokes, and high blood pressure. Early diagnosis and effective treatment are essential for improving patient outcomes. Explore cardiovascular disease research and diagnostic tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Infectious DiseaseInfectious disease diagnostics refers to the isolation and identification of causative agents, such as viruses, bacteria or fungi. Diagnostic tests include bacterial culture, microscopy, chemistry assays, molecular diagnostics and MALDI-TOF. Tests can be carried out in the laboratory or at the point-of-care.CannabinoidsCannabinoids are compounds found in cannabis that have therapeutic effects, such as pain relief, anti-inflammatory properties, and potential neuroprotective benefits. Research into cannabinoids is growing, particularly in the fields of pain management, neurological diseases, and cancer treatments. Browse our peer-reviewed product directory to find the best cannabinoid research tools, compare products, check reviews, and get pricing directly from manufacturers.CannabisProtein BiologyThe analysis of protein expression, identity and function is vital for many areas of life science research and drug discovery. Some of the most commonly used techniques in protein analysis include Western blotting, electrophoresis and mass spectrometry.

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