Trends in Drug Discovery: Antibody Engineering, Protective Antibody Treatments, Streamlining Antibody Discovery & More!

Find all the latest developments in antibody engineering and June’s top content from our drug discovery community

27 Jun 2019
Holly McHugh
Administrator / Office Personnel

Editorial article

This past month, we have featured some particularly exciting developments in antibody engineering, discovery and treatments. Here, we bring you all the latest news, techniques and technological developments from our Drug Discovery community, from high-speed phage-display technology to protective antibodies against viral outbreaks, to streamlining antibody discovery. Plus, as the month draws to a close, our editors are covering all the biggest technologies stories breaking at SLAS Europe 2019 in Barcelona.

SPECIAL FEATURE: Antibody Engineering

Discover the latest techniques and technologies advancing antibody engineering in our new special feature and meet the scientist using high-speed phage-display technology to bridge the gap between biomarker discovery and antibody development and meet the increasing demand for new recombinant antibodies.

Read special feature >>

Pandemic Prevention

In a concerted effort to ensure effective medical countermeasures in the event of a global viral outbreak, scientists from the Vanderbilt Vaccine Center are working on developing protective antibody treatments as complements to vaccines. Find out more about their groundbreaking work in this exclusive interview.

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Streamlining Antibody Discovery

With breakthroughs in molecular engineering and antibody humanization, monoclonal antibodies (mAbs) are one of the fastest growing classes of biopharmaceuticals for most clinical indications. Download this application note to find out how the Intellicyt® iQue Screener platform can streamline your antibody discovery workflow.

Download application note >>

Understanding Protein Interactions

Understanding protein-protein interactions (PPI) and their specific functions underpins basic molecular research as well as the development of novel drugs. Download this eBook for examples of robust, reproducible protein interaction assays.

Download eBook >>

No More Blurry Images

Fed up of blurry images when examining 3D specimens? Find out how cutting-edge Computational Clearing technology from Leica Microsystems resolves the longstanding challenge of blurry contrast when imaging thick sections.

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SLAS Europe 2019

SLAS Europe 2019, held in Barcelona between June 26-28, gives life sciences and drug discovery professionals the opportunity to learn about the latest developments in instrumentation, assays, and diagnostics through interactive scientific presentations, live demonstrations, and networking opportunities.

Technology highlights:

Peak Analysis & Automation (PAA) showcases new and improved integrated robotic systems, such as the S-LAB automated plate handler S-CEL laboratory work cells.

Find out more >>

Thermo Fisher Scientific showcases new generation of automated incubators, promising a robust and reliable culture solution for cell-based pharmaceutical applications.

Find out more >>

Keep an eye on our dedicated SLAS Europe 2019 feature page for more exciting news from the event, including exclusive video interviews with leading scientists and technology innovators.

Visit feature page >>

Latest Reviews About the Lab Technology You Use

Don't just take our word for it, read reviews left by scientists to help you choose the best instruments for your lab, or share your opinion to help your peers by writing your own review today. Read one of our latest reviews below by Cyro Zucarino, from Ginásio Carioca Anísio Teixeira, about the Octet Red384 by ForteBio.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Therapeutic AntibodiesTherapeutic antibodies are antibodies engineered for use in treating diseases. They can be designed to target specific antigens, blocking harmful interactions or modulating immune responses. Therapeutic antibodies are critical in treating conditions like cancer, autoimmune disorders, and infectious diseases. Explore the best therapeutic antibody products in our peer-reviewed product directory; compare options, check reviews, and get pricing directly from manufacturers.Engineered AntibodiesEngineered antibodies are modified to enhance specificity, stability, and functionality for therapeutic and diagnostic applications. These antibodies are central to immunotherapy and biomarker detection. Compare engineered antibody solutions in our directory to find top products and reviews.Protein InteractionsProtein interactions are essential for understanding cellular processes, as proteins work together to carry out biological functions. Studying protein interactions can provide insights into disease mechanisms, drug development, and cell signaling pathways. Explore the best tools for protein interaction research in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.3D Imaging3D imaging technologies allow for the visualization and analysis of three-dimensional structures at high resolution. These systems are used in fields like molecular biology, material science, and medical diagnostics. 3D imaging can be applied to visualize cells, tissues, and organs, providing valuable insights into their structure and function. Browse our peer-reviewed product directory to find the best 3D imaging solutions, compare products, check reviews, and get pricing directly from manufacturers.
Trends in Drug Discovery: Antibody Engineering, Protective Antibody Treatments, Streamlining Antibody Discovery & More!