Top new resources to advance your immuno-oncology research

Exclusive interviews, free downloads, the latest methods and much more to help support your immuno-oncology research

12 Nov 2020
Sophie Ball
Publishing / Media

Editorial article

As part of our new special feature, we've pulled together a selection of top new resources to help advance your immuno-oncology research. Discover the importance of robust methodologies for finding therapeutic antibodies, find out about the development of a knockout CRISPR-mediated gene editing capability, accelerate your pre-medical research with HLA-typed cells, and much more.

High-quality antibody generation for the immuno-oncology sector

Debby Kruijsen highlights the importance of high-throughput and robust methodologies, such as those provided by the iQue3 advanced flow cytometry platform from Sartorius, for finding ‘needle-in-the-haystack’ therapeutic antibodies.

Read article

The full potential of arrayed CRISPRko screening in Bregs

In this scientific poster, Horizon Discovery illustrates the development of a knockout CRISPR (CRISPRko)-mediated gene editing capability to investigate regulatory B cell (Breg) biology.

Download poster

Evolution of neuronal & glial tau isoforms in CTE

Dr. Jonathan Cherry discusses his work using the Vectra Polaris imaging system from Akoya Biosciences to study the immune profile of brain tissue suffering from chronic traumatic encephalopathy.

Watch video

Accelerate pre-clinical research with HLA-typed primary cells

Dr. Manish Kumar discusses human leukocyte antigen (HLA) genetics, typing, nomenclature, and applications in pre-clinical research, highlighting the broad range of high-quality HLA-typed cells offered by PromoCell.

Watch video

Rapid drug screening accelerates research for personalized medicine

Effectively identify, characterize, and evaluate engineered CAR T cells for cancer immunotherapy with this combined flow cytometry and impedance‑based real-time cell analysis workflow from Agilent Technologies.

Download info

How to study potential targets for immunotherapy

This comprehensive guide from Bio-Techne details some of the current and emerging immune checkpoint molecules that are being investigated as potential targets for cancer immunotherapy.

Download eBook


More exclusive interviews:

  • Predicting patient response to immunotherapy treatment: Dr. Ofer Sharon discusses a new cancer research platform designed to improve patient outcomes, cut costs, and minimize unnecessary adverse events. Read article>>
  • Examining infiltrating helper T cells: Automated cell counting saves time for immuno-oncology experiments: Learn how one immunology lab upgraded its cell counter to discriminate cells in a mixed population and streamline viability counts. Read article>>
  • A revolution in scientific collaboration: Dr. James Evans explains how his expert team helps other drug discovery companies grow and succeed, and highlights the power behind scientific collaboration, sharing ideas, and teaming up to win. Read article>>

Other resources in cancer research:

  • Cell imaging technology: In this eBook, we provide useful resources to help simplify your choice when it comes to purchasing your next cell imager. Download eBook>>
  • How to buy hematology analyzers and stainers: In this eBook, we present the different approaches to complete blood counts (CBC) and stained blood smear analysis, as well as important considerations to help guide your choice of instrumentation for the clinical hematology lab. Download eBook>>
  • Gene modulation in primary human immune cells: In this upcoming SelectScience webinar, immunology expert Dr. Verena Brucklacher-Waldert, Horizon Discovery, will share successful strategies for the manipulation of genes within physiologically relevant human immune cells. Register for Free>>

Your recommendations:

Take a look at what other researchers and scientists all over the world are saying about the latest equipment and technologies in cancer research. Jun Zhang shared their opinion on the Intellicyt iQue3 by Sartorius:

Find more news and resources in the Immuno-Oncology special feature>>

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.Therapeutic AntibodiesTherapeutic antibodies are antibodies engineered for use in treating diseases. They can be designed to target specific antigens, blocking harmful interactions or modulating immune responses. Therapeutic antibodies are critical in treating conditions like cancer, autoimmune disorders, and infectious diseases. Explore the best therapeutic antibody products in our peer-reviewed product directory; compare options, check reviews, and get pricing directly from manufacturers.TherapeuticsTherapeutics are treatments designed to alleviate or cure diseases. These include pharmaceuticals, biologics, and gene therapies, which work by targeting specific disease mechanisms. Advances in personalized medicine and biologics offer new hope for patients with conditions that were previously difficult to treat. Browse our peer-reviewed product directory to find therapeutic solutions for various diseases; compare products, check user reviews, and get pricing directly from manufacturers.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.