Latest Advances in Cell-Based Assays: Special Feature

From flow cytometry and kinetic analysis to porous membranes and liquid handling, find out the latest techniques and technologies advancing cell-based assays

3 May 2020
Carrie Haslam
Associate Editor

Editorial article

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Advances in science and technology have been continually improving how cell-based assay platforms are developed and applied in academia and industry. From flow cytometry and kinetic analysis to porous membranes and liquid handling, in this new special feature, we explore some of the latest techniques and technologies emerging in the field of cell-based assays.
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Flow cytometry: Dealing with the demands of modern drug discovery

Find out how advanced flow cytometry is meeting the demands of today's drug discovery pipelines by facilitating rapid analysis of complex cell-based models, in this white paper from Sartorius.

Download Paper

Vacuum filtration: Perform multiple filtrations simultaneously and save time

Discover how you can save time in your lab with the new vacuum filtration system from Sartorius, designed to cater for 50 mL volumes and speed up the cell line development process like never before.

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Porous membranes: How can you simplify and enhance your cell analysis?

Learn how Millicell® inserts from Merck foster in vivo-like cell growth conditions to better support your research goals and discover the advantages of using microporous membranes in the labs.

Download Method

Kinetic assays: Upgrade your ligand bias detection method using dual-channel assays

Discover the latest approaches used for effective kinetic analysis and find out how the CLARIOstar from BMG LABTECH can help you reliably detect agonist bias with more simplicity than ever.

Download Method

Cell incubation: A new solution to your liquid handling process

Enhance your incubation processes by taking a look at the new solution for automated incubation. Learn how the compact INHECO SCILA platform instrument can reliably control temperature, atmosphere and CO2.

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Cell culture: Is contamination compromising your data?

Find out how the Cytomat 10 automated incubator with a fully automated thermal decontamination system can advance your lab and help you achieve optimum cell culture and high-capacity cell growth.

Download Method

Video interview with leading scientists:

Discover interviews with leading scientists in cell-based assay research below:

  • How X-ray microscopy can be used to visualize viral mechanisms in living cells: Maria Harkiolaki at Diamond Light Source discusses how X-ray microscopy can effectively track viral replication and infection, and explores her role in designing user-friendly microscopes Watch the interview >>
  • Discover how new biomicrofluidic devices can be used for intracellular delivery: In this video, Dr. Aram Chung at Korea University discusses his groundbreaking work fabricating microscale fluid flow devices for biomedical intracellular delivery, offering substantial benefits and new solutions to both biologists and physicians. Watch the interview >>
  • Are you getting the most out of your image-based data? Dr. Anne Carpenter, Institute Scientist and Imaging Platform Senior Director, Broad Institute of MIT and Harvard, explains how her work aims to bridge the gap between biology and computational sciences by providing the software and strategies to get the most out of image-based data.Watch the interview>>
  • Upgrade your ELISA by reducing testing turnaround times with the high-capacity EUROLabWorkstation: In this video, Justin Waldron, marketing manager for EUROIMMUN US, describes the new EUROLabWorkstation ELISA, a high-throughput, high-capacity ELISA processor that promises efficient sample loading and fast turnaround times. Watch the interview>>

Downloadable resources:

From cell culture workflows to cellular imaging, download the latest information here:

  • Ultimate Cell Culture Workflow Compendium: This application compendium pulls together everything you need to ensure successful cell culture in your lab, including a range of compatible products and guides on how to use them most effectively. Download method>>
  • Services for expression, purification, and scale production of proteins and immunoassays: In this application note, The Native Antigen Company provides insight into its key contracts and custom services, including construct design and cloning, protein expression, protein purification, antibody generation, and assay development. Download method>>
  • Cellular imaging insights: In this exclusive eBook, Molecular Devices provides an overview of the new tools that can be used to better understand complex imaging models. Download method>>

Your recommendations:

Don't just take our word for it, see what researchers around the world are saying about the products they use! Lauren Zavan from La Trobe University shared her opinion of the CLARIOstar® Plus Multi-mode Microplate Reader by BMG LABTECH:

For more of the latest cell-based assay news, straight to your inbox, become a member of SelectScience for free today>>

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Cell Adhesion AssaysCell adhesion assays are used to quantitate attachment and analyze the molecular mechanisms for extracellular matrix adhesion, cell migration and sensitivity to inhibitors. Find the best cell adhesion assay equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunoassayImmunoassays are laboratory tests that utilize antibody-antigen interactions to detect specific substances. They are widely used in diagnostics for detecting diseases, drug testing, and environmental monitoring. These assays offer rapid, sensitive, and precise detection of biomarkers, making them invaluable in clinical and research labs. Browse our peer-reviewed product directory to compare immunoassay systems, read user reviews, and get pricing directly from manufacturers.Cell-Based PlatformPharmacokineticsAssay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.Cell Based AssaysCell-based assays use living cells to measure biological responses to various treatments or stimuli. They are essential for drug discovery, toxicology testing, and understanding cellular mechanisms. These assays are used to assess cell viability, proliferation, gene expression, and other cellular activities. Browse our peer-reviewed product directory to find the best cell-based assay tools and reagents, compare products, read customer reviews, and get pricing directly from manufacturers.