Drug Discovery Round-Up: T Cell Therapy, Therapeutic Monoclonal Antibodies, 3D Cell Culture, Plus Much More!

Find all the latest developments and top content in our drug discovery community over the past month

29 May 2019
Holly McHugh
Administrator / Office Personnel

Editorial article

In this month’s drug discovery round-up, we bring you the latest advancements in personalized T-cell therapy, application compendiums for automated liquid handling and therapeutic monoclonal antibodies, video interview highlights from AACR 2019, and introduce our two new channels on The Scientists’ Channel. Keep up to date on the latest trends and hot topics to advance your drug discovery research.

Personalized T-Cell Therapy Using Neoantigens

Alison Tarke and her team at PersImmune have adopted a unique strategy for improving patient response to adoptive T cell therapy in acute myeloid leukemia by using patient specific ‘neoantigens’ present in a tumor to achieve more potent personalized cancer killing.

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3D Cell Culture Methods and Resources

Learn about the most recent developments in 3D cell culture and biology, including hot topics such as assays for cell characterization, magnetic nanoparticles for culture analysis and uniform spheroid formation, and check out our pick of the best videos and resources in the field.

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Fluorine in the Chemical Industry

Fluorine is most commonly known for its dental hygiene properties, but do you know the extent of its potential in other real-world applications? Learn how research chemists use analytical technology to support the design of novel fluorine-based compounds that transforms our lives.

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AACR Video Interview Highlights

We've compiled a list of our top video interviews with scientific experts from the 2019 American Association for Cancer Research (AACR) annual meeting, covering topics such as characterizing the biomolecular signatures of cancer, real-time analysis of cell heterogeneity, and highlights from the conference president.

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Automated Liquid Handling Application Compendium

Sample preparation in metabolomics, next-generation sequencing, cell and protein analysis can be a laborious and time-consuming process with limited reproducibility. Discover how one automated liquid handling platform enables high-throughput screening and reproducible results in a range of applications, in this downloadable guide.

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Therapeutic Monoclonal Antibody Application Compendium

Therapeutic monoclonal antibodies now offer one of the most successful therapeutic strategies for both hematologic cancers and solid tumors. Download this application compendium to find important solutions for the effective discovery and development of therapeutic monoclonal antibodies, plus new cutting-edge technologies for effective antibody characterization.

Download guide >>

The Scientists' Channel: NEW VIDEO CHANNELS

SLAS

SLAS is a community for over 19,000 scientists and technology professionals which hosts a thriving International Conference & Exhibition annually & has recently launched a new European showcase. Now it has its own video channel too, featuring leading scientists discussing their research and sharing the latest developments in their field.

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ELRIG

ELRIG is a UK-based not-for-profit organisation that provides outstanding up-to-the-minute knowledge to the life sciences and drug discovery community during scientific meetings and conferences. The events bring together academic and biopharma industry experts from around the world to exchange ideas and information to accelerate scientific research. It also recently launched its very own video channel, featuring exclusive video interviews with leading industry experts.

Visit channel >>

Latest Reviews About the Lab Technology You Use

Don't just take our word for it, read reviews left by scientists to help you choose the best instruments for your lab, or share your opinion to help your peers by writing your own review today. Read one of our latest reviews below by Alvaro Amorin from Stanford University for the LUNA-II™ Automated Cell Counter by Logos Biosystems, Inc.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Monoclonal AntibodiesMonoclonal antibodies (mAbs) are lab-made molecules that can bind to specific antigens on cells, making them highly effective in treating cancers, autoimmune diseases, and infections. These targeted therapies are transforming the treatment landscape for many conditions. Browse our peer-reviewed product directory to find monoclonal antibodies for research and clinical applications; compare products, check reviews, and get pricing directly from manufacturers.AutomationAutomation in laboratories and manufacturing processes enhances efficiency, precision, and scalability by reducing the need for manual intervention. It plays a critical role in improving productivity, minimizing human error, and accelerating workflows in fields like diagnostics, drug development, and industrial testing. Automation technologies include robotic systems, automated liquid handlers, and process control systems that streamline complex tasks and ensure consistent, reproducible results. Explore our peer-reviewed product directory to discover the best automation solutions, compare options, read user reviews, and get prices directly from manufacturers.Cell AnalysisThe analysis of cells allows researchers to understand the factors which contribute to cell health and function. These influencing processes can then be predicted and altered, leading to the development of medication and disease treatments.Cancer ResearchCancer research aims to understand the mechanisms of cancer development and progression to improve prevention, diagnosis, and treatment. From molecular biology to clinical trials, research spans a wide range of disciplines, including immunotherapy, targeted therapies, and drug discovery. Explore the best cancer research products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Therapeutic AntibodiesTherapeutic antibodies are antibodies engineered for use in treating diseases. They can be designed to target specific antigens, blocking harmful interactions or modulating immune responses. Therapeutic antibodies are critical in treating conditions like cancer, autoimmune disorders, and infectious diseases. Explore the best therapeutic antibody products in our peer-reviewed product directory; compare options, check reviews, and get pricing directly from manufacturers.AntibodiesAACRThe American Association for Cancer Research (AACR) is a leading organization focused on cancer research and treatment. It provides a platform for scientists, healthcare professionals, and industry leaders to share knowledge and collaborate in the fight against cancer.Liquid HandlingLiquid handling involves the precise transfer, mixing, and dispensing of liquids in laboratory settings. It is essential for accurate and consistent results in biological, chemical, and pharmaceutical research. Automated liquid handling systems improve efficiency and reduce human error in sample preparation and analysis. Explore liquid handling tools in our peer-reviewed product directory; compare products, read customer reviews, and get pricing directly from manufacturers.T Cells