Antibiotic Resistance – a Growing Threat to Food Safety?

31 Mar 2015
Lois Manton-O'Byrne, PhD
Executive Editor

Editorial article

Around the world, the concern over antibiotic resistance is growing, and everyone from doctors to politicians is getting involved in the debate. Antibiotic resistance is one of the biggest dangers of current times, as evidenced with US President Barack Obama’s recent pledge of $1.2bn to combat the threat.

Veterinary Antibiotics

Managing veterinary use of antibiotics is one of the key elements of tackling this growing crisis. To this end, $270m of the money pledged by the US Government has been earmarked for the Food and Drug Administration (FDA) specifically to combat the overuse of antibiotics in food production.

Indiscriminate medicating by producers for disease control rather than treatment has led to overuse, and the picture is further complicated by the use of medication to increase weight gain and performance. An estimated 70% of antibiotics produced in the USA are used in animal agriculture to accelerate animal growth and prevent diseases. This amount is estimated to be more than four times the amount of drugs used to treat human illness. (Source: www.ucsusa.org/food)

Antibiotic Resistant Pathogens

As pathogens evolve and become resistant to antibiotics, there is the potential for them to be transferred from animal food products to humans. This limits the options of disease treatment, not to mention the risk to humans of toxicity or allergies from antibiotic residues.

Authorities around the world have, as a result, set strict limits on the amounts of veterinary drugs that can be present in food products. Whether it’s international standards such as the WHO’s Codex scheme, regional standards such as the EU regulations or national requirements such as the USDA, authorities have established Maximum Residue Limits (MRL) for a wide range of drug residues in food products. This means food produce must be either free from or below particular levels of a whole host of medicinal compounds.

In the event of falling foul of standards, product recalls and fines may be the least of food producers’ worries. Restoring consumer confidence, once damaged, can be a much longer term issue. Indeed, disputes over the safety of particular compounds can quickly escalate to diplomatic levels triggering trade embargoes, with the Russian, EU and Chinese ban on beta-agonist fed meat being an example.

All of this makes issues affecting exporters of food products very complex. They need to be conscious of a multitude of regulations varying across markets. The ability to screen products effectively for multiple substances is key.

Randox Food Diagnostics’ Evidence Investigator, using Biochip Array Technology, offers a unique multi-analyte testing platform that will reduce labor costs, increase throughput and overall productivity. Detecting up to 22 analytes, with new technology now detecting up to 46 analytes, from a single sample in less than two hours and with less than 5% false positives and no false negatives, food producers can have confidence in results.

With the drive to tackle antibiotic resistance seeing regulations strengthened right across the world, it’s becoming increasingly clear that food companies will need to invest in technology to keep pace.

Ref: Antibiotic resistance and food safety

Article by Randox Food Diagnostics

Links

Tags

PCR and Thermal CyclingPolymerase chain reaction (PCR) kits and thermal cyclers are used for the in vitro amplification of DNA permitting subsequent analysis and experimental procedures. Explore a range of high-quality polymerase, primers and nucleotides or simplify your workflow with a PCR mastermix. Find reverse transcription PCR (RT-PCR) and cDNA synthesis kits for RNA products and libraries. Quantitatively measure the amplification of DNA with real-time PCR (qPCR) and droplet digital PCR (ddPCR) kits and systems, and discover automated PCR setup solutions to increase throughput. Alternative DNA amplification methods also include recombinase polymerase amplification (RPA) kits. Find the best PCR kits and thermal cyclers and purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Microarray AnalysisMicroarrays, also known as biochips, are used for the detection and analysis of multiple genes, proteins, antibodies, or biomarkers on a single microchip. This can reveal information on protein or gene expression, single nucleotide polymorphism (SNP), copy number variation (CNV), epigenetics and patient health in clinical diagnostic tests. Discover a range of microarray scanners and prefabricated antibody, protein, RNA and DNA microarrays for your analysis or consider creating your own custom microarrays with a microarray printer. Find the best microarray products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Food and Beverage AnalyzersFood and Beverage Analyzers are commonly used to provide information about the chemical composition, structure and physical properties of food materials.Food and Beverage ProcessingFood and Beverage Processing involves the preparation of food products for further analysis. Typical instrumentation includes blanchers, color sorters, cookers, grinders, and refrigeration. These are used to replicate the processes commonly used in the commercial preparation of food and beverages.QuEChERSThe QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) method is a streamlined approach that is used to extract multi-residue target compounds from food samples. It is most commonly used by analytical chemists studying pesticide residues in food.Pathogen DetectionPathogen detection is the process of identifying harmful microorganisms, including bacteria, viruses, and fungi, that can cause diseases. Accurate pathogen detection is critical for food safety, public health, and clinical diagnostics. Explore pathogen detection products in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.AntibioticsAntibiotics are substances that kill or inhibit the growth of microorganisms, such as bacteria and fungi. They are essential in the treatment of infections and in preventing disease spread. Explore antibiotics research and diagnostic tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Veterinary DrugsAntibiotic ResistanceAntibiotic resistance poses a significant threat to public health driving innovation and change through antibiotic stewardship efforts. Ongoing research and diagnostic efforts focus on new treatments and detection methods. Explore antibiotic resistance research and diagnostic tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.