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Overcoming the sensitivity vs. robustness trade-off in mass spectrometry

22 Jul 2025
Overcoming the sensitivity vs. robustness trade-off in mass spectrometry

Dr. Rowan Moore from Waters Corporation introduces the Xevo™ TQ Absolute XR Mass Spectrometer and explores how it can be used for a range of pharmaceutical, food and environmental applications, such as PFAS testing. Discover how this system eliminates the traditional compromise between sensitivity and robustness with the StepWave XR ion guide which has proven to maintain high sensitivity across tens of thousands of injections, even with the most challenging sample matrices.

This video was filmed at ASMS 2025, Baltimore, USA.

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Waters

Waters Corporation, the premium brand in the analytical instruments industry since 1958, creates business advantages for laboratory-dependent organizations by delivering practical and sustainable scientific innovation to enable significant advancements in such areas as: healthcare delivery, environmental management, food safety, chemical materials analysis, and water quality worldwide. Waters helps customers make profound discoveries, optimize laboratory operations, deliver product performance, and ensure regulatory compliance by providing a connected portfolio of separations and analytical science, mass spectrometry, laboratory informatics, as well as thermal analysis products.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Environmental Monitoring and TestingEnvironmental monitoring and testing uses handheld portable analyzers, kits, spectrometers or chromatography systems for air, water, soil, food and other sample testing. Useful features of analyzers such as BOD and COD include portability, easy calibration, automation and sensitivity.  Environmental test kits for pH, water, moisture, etc, should be accurate, sensitive, reliable, fast and easy to use.PFASQuality TestingQuality testing ensures that products meet required specifications and safety standards in various industries, including pharmaceuticals, food, and materials. It is essential for maintaining product quality and consumer safety. Explore quality testing tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.