Live Cell RNA Detection
23 Apr 2013In this video Don Weldon tells SelectScience about the new SmartFlare RNA Detection Probes from EMD Millipore. Don explains how live cell RNA detection is now possible, in a single incubation step using inert nanoparticle technology to specifically detect native RNA. He discusses some of the key benefits of this approach compared to existing techniques, such as real-time PCR and demonstrates how the technology works. Interview filmed by SelectScience at AACR 2013.
About the company
Merck
The Life Science business of Merck KGaA, Darmstadt, Germany, which operates as MilliporeSigma in the U.S. and Canada, has some 22,000 employees and 59 manufacturing sites worldwide, with a portfolio of more than 300,000 products focused on scientific discovery, biomanufacturing and testing services.
Related products
Request Quote for All Products
SmartFlare RNA Detection Probes
MerckSmartFlare Probes work by recognizing specific native RNA sequences within living cells, therefore there are many possible sequences that you could design to recognize your target of interest. Instead of lysed cells, switch to live cells. And while you’re at it, eliminate sample preparation and transfection steps all together. Live cell RNA detection is now possible, in a single incubation step using inert nanoparticle technology to specifically detect native RNA. And when you’re done, the probes exit the cells allowing you to perform downstream analyses with the same, unperturbed cells. Make the smart change!SmartFlare RNA Detection Probes are fueled by the NanoFlare technology developed by renowned chemist Dr. Chad Mirkin.What's Smart? Detect RNA expression in live cells for real time, physiologically relevant data Eliminate laborious, costly sample preparation Easy analysis on the fluorescent detection platform of your choice Nanoparticle based technology that allows cells to be used for downstream assays
