LC troubleshooting - All of my peaks are tailing! What should I do?
27 Apr 2021
Tailing peaks can be a problem when doing liquid chromatography (LC), and secondary silanol interactions are one of the causes. Here, using the example of basic drugs, Restek explains what causes them and cover a few steps that can be taken to minimize the effect of these secondary silanols on peak shape when troubleshooting.
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Restek Corp.
Restek is a leading developer and manufacturer of chromatography columns and accessories. We provide analysts around the world with the innovative tools they need to monitor the quality of air, water, soil, foods, pharmaceuticals, chemical, and petroleum products.
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