ioMicroglia in coculture with ioGlutamatergic Neurons

The widespread use of human induced pluripotent stem cell (hiPSC) derived mature cell types has been restricted by complex and suboptimal differentiation protocols. bit.bio novel cellular reprogramming approach supported by a uniquely engineered genetic switch, opti-ox, is able to largely overcome these restrictions. This proprietary technology enables homogeneous and efficient differentiation of entire hiPSC cultures through tightly controlled expression of selected transcription factors. opti-ox reprogramming enables the consistent manufacture of homogenous and mature hiPSCs derived functional cells within days, offering access to the highest quality cellular models with simple protocols.

‘bit.bio’ represents the two fields — coding and biology — that determine the Identity of every human cell. Ultimately, bits are the building blocks of code, just as cells are the building blocks of life. This is reflective of what Bit Bio does: precise reprogramming of human stem cells. Our mission and focus are to enable a new generation of therapies through democratising access to consistent and functional human cells. This will improve research and drug discovery, lower the cost and extend the application of cell therapies.