Open source software for multiplex staining & image analysis
23 Oct 2024
Dr. Sarah McArdle presents on open source software for quantitative image analysis, focusing on multiplex staining for high dimensional analysis. She explains the RareCyte Orion microscope and its image acquisition process. The discussion covers the advantages of open source software, challenges in analyzing large datasets, and the importance of validating staining quality.
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RareCyte, Inc
RareCyte is an innovative precision biology company that has developed technologies and end-to-end integrated platforms enabling advances in oncology, immuno-oncology, maternal-fetal health, and cell and gene therapy.
As a leading biotechnology company, our team of scientists and engineers are continuously dedicated to design products and provide services which advance precision medicine and biomedical research, ensure successful clinical development programs and contribute to companion diagnostic development. Our solutions span end-to-end instrumentation and panels in Liquid Biopsy, Spatial Biology, and a Precision Biology Services division for clinical trials to drug development.
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Orion Multiplex Imaging Instrument
RareCyte, IncThe Orion Platform delivers spatial biology and cellular phenotyping at a speed and resolution needed for translation from research to the clinic. It utilizes single round immunofluorescence staining and imaging of standard FFPE or fresh frozen tissue to deliver subcellular quantitation of biomarker targets across a whole slide in only a few hours. Combining speed and resolution with the additional benefits of industry-standard H&E and IHC modes, comprehensive phenotypic profiling of patient cohorts can be generated for characterization of tissue architecture, tumor heterogeneity, and the immune response. Use your own antibodies, run panels from an extensive biomarker list, or engage RareCyte services for custom panels and programs.