Video ReviewsLife Sciences

Building a bridge between organoid research and drug discovery

3 Mar 2025
Building a bridge between organoid research and drug discovery

Step inside the world of next-generation 3D cell culture with Dr Elad Katz, founder of Navigate Precision Biology, a spin-out from the University of Dundee. In this interview, Dr Katz shares how their groundbreaking NaviPlate system generates 384 identical organoids in a single microplate — a powerful, automation-friendly platform for studying disease models and accelerating drug discovery.

Discover how Dr Katz relies on the PHERAstar FSX microplate reader to push the boundaries of organoid research, using fluorescence intensity to analyze life/death assays with as few as 500 cells per well. From cancer and bone microtissues to heart, kidney, and lung organoids, learn how high-throughput, ultra-sensitive detection is driving innovations in fibrosis research, calcium flux oscillations, and beyond.

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BMG LABTECH

BMG LABTECH - The Microplate Reader Company

BMG LABTECH has been committed to providing high quality microplate readers for academic and high-throughput laboratories since 1989, and has earned the reputation of being a technology leader through ongoing innovations and by carefully listening to the needs of the scientific community.

BMG LABTECH has developed the widest range of dedicated, multi-mode, life science, and HTS microplate readers available.

The CLARIOstar® is a multi-mode, high-performance microplate reader with revolutionary monochromator technology. The patent-pending LVF Monochromators™ give the CLARIOstar filter-like performance combined with the flexibility of monochromators.

BMG LABTECH also provides the perfect microplate readers for High-Throughput Screening, assay development, and high-end applications. The PHERAstar® FSX is designed to read multiple detection modes including UV/Vis absorbance spectra, fluorescence intensity, FRET, fluorescence polarization, time-resolved fluorescence, HTRF, LANCE, DELFIA, AlphaScreen / AlphaLISA, luminescence and BRET in all plate formats up to 3456.

The Omega Series are the only life science microplate readers with Tandem Technology - ultra-fast UV/Vis spectrometer based absorbance and highly sensitive filter-based detection for measuring fluorescence and luminescence. These multi-mode microplate readers are also capable of reading TR-FRET assays such as HTRF and LanthaScreen as well as AlphaTechnology based assays.

4.7/5.0
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Microplate Readers / DetectorsMicroplate readers are used to automate the detection and analysis of labeled or label-free components in microplates during assays or live-cell monitoring. Microplate readers are generally distinguished by their mode of detection. Types include absorbance, luminescence, fluorescence intensity, fluorescence polarization, TRF / FRET and multimode microplate readers. Microplate readers deliver a high throughput of samples by reading multiple wells simultaneously, with the 96-well format the most commonly used. As a result, microplate readers are often used in the drug discovery, bioassays, research and pharmaceutical industries for screening applications. Microplate loading can also be automated, with robotic microplate stackers to increase throughput. Find the best microplate readers in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Organoids3D Cell CultureCulturing cells in three dimensions allows more physiologically relevant observations to be made regarding cellular interactions and gene expression. 3D models provide a more accurate representation of cells in vivo and are more stable than 2D cultures, making them very useful for long-term studies.Disease ModelsHigh ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.