Automatic single cell tracking with HoloMonitor App Suite: Accurate, real-time live cell analysis
19 Sept 2021
The cell-friendly HoloMonitor® cell culture microscope lets you study your cells directly inside a normal incubator, completely label-free. The HoloMonitor Single Cell Tracking assay automatically tracks the cells in your culture over time. It provides you with comprehensive data on, for example, cell movement, cell division, and cell death, both for every single cell but also for the whole cell population.
This video shows a 48-hour time-lapse with L929 mouse fibroblasts. All cells in the field of view are automatically tracked, and non-treated cells are compared with the same cells treated with the chemotherapeutic drug colcemid. It is evident that the drug not only prevents the cells from dividing but also lowers their movement to a minimum.
About the company
Phase Holographic Imaging (PHI)
Phase Holographic Imaging AB (PHI) provides researchers in academia and the life science industry with products for live-cell kinetic studies. PHI’s time-lapse cytometer, the HoloMonitor® system, is based on our core technology holographic microscopy. Since introducing the first instrument in 2011, PHI now offers a range of products for label-free, long-term quantitative analysis of living cell dynamics, circumventing the drawbacks of traditional methods requiring toxic stains. Headquartered in Lund, Sweden, PHI trades through a network of international distributors.
The HoloMonitor system is a versatile tool providing detailed information about the life cycle and behavior of living, or dying, cells to scientists all over the world. Focus areas include basic cell research as well as the development of more efficient treatment strategies for cancer and other diseases. Committed to promoting the science and practice of time-lapse cytometry, PHI is continuously developing new products and applications in close collaboration with scientific expertise.
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HoloMonitor® M4 Live Cell Analysis System
Phase Holographic Imaging (PHI)The HoloMonitor ® live cell imaging system enables long-term non-invasive analysis of cell cultures within your standard incubator. Cell biologists worldwide use PHI’s label-free cell imager to automatically obtain accurate live-cell morphology, migration, and proliferation data as well as multi-well time-lapse videos, down to a single-cell level in real-time.
