A new era of biomarker controls
4 Jun 2024
Amay Dankar shares how TruCytes™ Biomarker Controls from Slingshot Biosciences are high-performing ready-to-use controls for the positive detection of specific surface biomarkers. Discover how this flexible technology is helping advance cell therapy development by providing flexible platforms for reagent validation, quality control, and potency testing.
This video was filmed at CYTO 2024.
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TruCytes™ TBNK Lymphocyte Subset Control
Slingshot BiosciencesTruCytes™ TBNK synthetic cells are lyophilized cell mimics that feature T cell, B cell and NK cell markers with scatter coordinates (FSC and SSC) that closely mimic lymphocyte, monocyte, and granulocyte populations. This product is intended to provide positive and negative signal detection for specific surface biomarkers targeted by specific antibodies. Biomarkers: CD4+ T-cells: CD45+, CD3+, CD4+ CD8+ T-cells: CD45+, CD3+, CD8+ B-cells: CD45+, CD3-, CD19+ NK cells: CD45+, CD3-, CD16/56 Classical monocyte: CD45+, CD14+ Granulocytes: CD45+ Benefits: Positive biomarker controls for CD45, CD3, CD4, CD8, CD19, CD56, CD16, CD14 and CD45 Enhanced consistency and reliability versus traditional controls (fresh primary cells, frozen controls, and lyophilized products) Exceptional product stability versus all biologically-derived cellular controls