Workflow to Measure Plasma Renin Activity and Aldosterone for Clinical Research Using Automated On-line Extraction Coupled to LC-MS/MS
11 Dec 2017Researchers studying the renin-angiotensin aldosterone system need efficient ways to measure renin activity and aldosterone concentration in plasma sample preparations. This application note presents an automated on-line extraction workflow coupled to LC-MS/MS to simplify sample preparation for this procedure.
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Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.Clinical StudyProspective biomedical or behavioral research studies on human subjects, following tests in animals, that are designed to answer specific questions about novel vaccines, drugs, treatments, dietary supplements, devices or new ways of using known interventions, generating safety and efficacy data.LC-MSLiquid Chromatography-Mass Spectrometry (LCMS) is a powerful analytical technique that combines the separation power of liquid chromatography with the detection capabilities of mass spectrometry. It is widely used for qualitative and quantitative analysis of complex mixtures in pharmaceuticals, proteomics, and environmental studies. Browse our peer-reviewed product directory to find the best LCMS systems, compare products, check reviews, and get pricing directly from manufacturers.