Understanding the complex landscape of bioconjugates

31 Oct 2025
Cameron Smith-Craig
Cameron Smith-Craig
Pharma and Applied Sciences Editor

Bioconjugates are a rapidly expanding therapeutic modality demonstrating tremendous benefit for cancer patients already, and with significant promise in inflammatory, infectious and rare diseases. Key to the successful development of bioconjugates is the selection of an appropriate conjugation strategy.

In this eBook, Dr. Nicolas Camper, Vice President, and Dr. Petra Dieterich, Senior Vice President & Scientific Leader, Abzena, review and discuss the main categories of therapeutic bioconjugates, focusing on their key required characteristics or target product profile (TPP). Including, key considerations for selecting the most appropriate conjugation strategy for each application and insights into technological options along with real-world examples of bioconjugates in clinical development and in-market.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.Drug DeliveryDrug Delivery refers to dosage form, route of administration, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect. Drug delivery is often approached via the biopharmaceutical or small molecule drug's formulation, but it may also involve medical devices or drug-device combination products. Considerations include instrumentation, software and services. CRO ServicesExplore the comprehensive range of services offered by Contract Research Organizations (CROs) to streamline drug development and clinical research. From preclinical studies to regulatory support and clinical trials, CROs provide expert solutions that help pharmaceutical and biotech companies bring products to market faster and more efficiently.Antibody Drug ConjugatesAntibody conjugation
Understanding the complex landscape of bioconjugates